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Related Concept Videos

lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA (lncRNA)...
lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA (lncRNA)...
Types of RNA01:20

Types of RNA

Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in regulating gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA Performs Diverse...
Types of RNA01:23

Types of RNA

Overview
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in the regulation of gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA...
Types of RNA01:23

Types of RNA

Overview
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in the regulation of gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA...
Types of RNA01:20

Types of RNA

Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in regulating gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA Performs Diverse...

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Related Experiment Video

Updated: May 10, 2026

RNA Pull-down Procedure to Identify RNA Targets of a Long Non-coding RNA
09:36

RNA Pull-down Procedure to Identify RNA Targets of a Long Non-coding RNA

Published on: April 10, 2018

Identification and function of long non-coding RNAs.

Robert S Young1, Chris P Ponting

  • 1MRC Human Genetics Unit, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK. robert.young@igmm.ed.ac.uk

Essays in Biochemistry
|July 9, 2013
PubMed
Summary
This summary is machine-generated.

Eukaryotic cells produce thousands of long non-coding RNAs (lncRNAs), molecules with uncertain biological relevance. Research suggests many lncRNAs regulate gene expression and are implicated in cancer, warranting further investigation.

Related Experiment Videos

Last Updated: May 10, 2026

RNA Pull-down Procedure to Identify RNA Targets of a Long Non-coding RNA
09:36

RNA Pull-down Procedure to Identify RNA Targets of a Long Non-coding RNA

Published on: April 10, 2018

Area of Science:

  • Molecular Biology
  • Genomics
  • RNA Biology

Background:

  • Eukaryotic cells generate numerous non-coding RNAs.
  • Long non-coding RNAs (lncRNAs), longer than 200 nucleotides, are the least understood.
  • The biological significance of lncRNAs remains largely undetermined.

Purpose of the Study:

  • To explore the functional roles of long non-coding RNAs (lncRNAs).
  • To investigate the potential involvement of lncRNAs in cellular processes and disease.

Main Methods:

  • Genome-wide sequencing projects to identify lncRNA loci across species.
  • Functional genomic scans, including evolutionary and expression analyses.
  • Experimental investigation of selected lncRNAs.

Main Results:

  • Thousands of lncRNA loci have been identified in diverse species.
  • Evolutionary and expression data indicate potential functional roles for many lncRNAs.
  • A small number of studied lncRNAs are involved in gene expression regulation.
  • Some lncRNAs have been linked to cancer development.

Conclusions:

  • lncRNAs represent a significant class of non-coding genes.
  • Further experimental research is crucial to elucidate the importance and functions of lncRNAs.
  • lncRNAs may play critical roles in gene regulation and disease pathogenesis.