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An improved cation exchange HPLC method for the measurement of serum creatinine
1Department of Clinical Chemistry, East Birmingham Hospital, Bordesley Green East, UK.
Annals of Clinical Biochemistry
|May 1, 1990
Abstract:
An improved HPLC method for the measurement of serum creatinine is described. Separation is effected using a strong cation exchange column at pH 4.7. Analytical recovery, precision and linearity are satisfactory, and the method correlates well with a kinetic Jaffé procedure. The method provides a means of accurately measuring creatinine and may be of use in the investigation of interference in creatinine assays.