The assignment of the genes coding for human complement components C6 and C7 to chromosome 5
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S J Jeremiah1, C M Abbott, Z Murad
1MRC Human Biochemical Genetics Unit, Galton Laboratory, University College London.
Annals of Human Genetics
|May 1, 1990
Abstract:
A panel of 19 somatic cell hybrids was tested for the presence of human sequences coding for complement components C6 and C7 by restriction enzyme digestion and Southern blots probed with human C6 and C7 cDNA probes. C7 was also detected by amplifying part of the human gene in hybrid DNA using the polymerase chain reaction. Detection of human C6 and C7 was completely correlated with the presence of chromosome 5.