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Updated: May 10, 2026

Sheathless Capillary Electrophoresis–Mass Spectrometry for Metabolic Profiling of Biological Samples
Published on: October 1, 2016
Direct coupling of supported liquid membranes to capillary electrophoresis for analysis of complex samples: a
1Institute of Analytical Chemistry of the Academy of Sciences of the Czech Republic, vvi, Brno, Czech Republic. kuban@iach.cz
Abstract:
This tutorial provides an overview of direct coupling of extraction techniques based on supported liquid membranes (SLMs) to capillary electrophoresis (CE) for treatment and subsequent analysis of complex samples. Pros and cons of using each of the described instrumental arrangement are addressed and where relevant, comments with personal experience of the authors are presented. Solid porous membrane based extraction techniques coupled directly to CE are also presented in this tutorial and a comprehensive discussion is included on their instrumental set-ups and their possible adaptation for use with SLMs.
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