Related Experiment Video

Updated: May 10, 2026

Development of Combinatorial Therapeutics for Spinal Cord Injury using Stem Cell Delivery
05:13

Development of Combinatorial Therapeutics for Spinal Cord Injury using Stem Cell Delivery

Published on: June 7, 2024

Combinatory treatments needed for spinal cord injury

Lars Olson1

  • 1Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.

Experimental Neurology
|July 9, 2013
PubMed
Summary

No abstract available in PubMed .

More Related Videos

Combining Peripheral Nerve Grafting and Matrix Modulation to Repair the Injured Rat Spinal Cord
20:14

Combining Peripheral Nerve Grafting and Matrix Modulation to Repair the Injured Rat Spinal Cord

Published on: November 20, 2009

Experimental Strategies to Bridge Large Tissue Gaps in the Injured Spinal Cord after Acute and Chronic Lesion
09:14

Experimental Strategies to Bridge Large Tissue Gaps in the Injured Spinal Cord after Acute and Chronic Lesion

Published on: April 5, 2016

Related Experiment Videos

Last Updated: May 10, 2026

Development of Combinatorial Therapeutics for Spinal Cord Injury using Stem Cell Delivery
05:13

Development of Combinatorial Therapeutics for Spinal Cord Injury using Stem Cell Delivery

Published on: June 7, 2024

Combining Peripheral Nerve Grafting and Matrix Modulation to Repair the Injured Rat Spinal Cord
20:14

Combining Peripheral Nerve Grafting and Matrix Modulation to Repair the Injured Rat Spinal Cord

Published on: November 20, 2009

Experimental Strategies to Bridge Large Tissue Gaps in the Injured Spinal Cord after Acute and Chronic Lesion
09:14

Experimental Strategies to Bridge Large Tissue Gaps in the Injured Spinal Cord after Acute and Chronic Lesion

Published on: April 5, 2016

Related Concept Videos

Spinal Cord Injury ll: Pathophysiology01:14

Spinal Cord Injury ll: Pathophysiology

Spinal cord injury progresses through two interconnected phases: primary injury and secondary injury.Primary InjuryPrimary injury happens at the moment of trauma and involves immediate mechanical damage to the spinal cord.Compression happens when broken vertebrae, herniated discs, or accumulating blood (such as a hematoma) press directly against the spinal cord, distorting its normal shape and function. In cases of contusion, the cord is bruised by a blunt force (like penetrating injuries or...
Secondary Spinal Cord Injury llI: Pathophysiology01:25

Secondary Spinal Cord Injury llI: Pathophysiology

Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...

Articles linked to this work by shared authors, journal, and citation graph.

PT320, a GLP-1 receptor agonist, mitigates nucleus accumbens-associated depression- and anxiety-like behaviors in MitoPark mice of Parkinson's disease.

Journal of Parkinson's disease·2026

Analyses of Nogo-Family Genes in Mouse and Human Microglia Omics Datasets Identify LINGO1 as a Candidate Drug Target in Alzheimer's Disease.

Current neuropharmacology·2025

Serotonergic Regulation of Synaptic Dopamine Levels Mitigates L-DOPA-Induced Dyskinesia in a Mouse Model of Parkinson's Disease.

Journal of Parkinson's disease·2024

Attenuating mitochondrial dysfunction and morphological disruption with PT320 delays dopamine degeneration in MitoPark mice.

Journal of biomedical science·2024

Spatio-temporal brain invasion pattern of Streptococcus pneumoniae and dynamic changes in the cellular environment in bacteremia-derived meningitis.

Neurobiology of disease·2024

Mitochondrial Dysfunction and Protein Homeostasis in Aging: Insights from a Premature-Aging Mouse Model.

Biomolecules·2024

Astrocytic TRPC6 protects against cerebral ischemia-reperfusion injury by inhibiting cGAS-STING pathway.

Experimental neurology·2026

Astrocytes in Parkinson's disease: Beyond support, toward therapy.

Experimental neurology·2026

Longitudinal magnetic resonance imaging and spectroscopy in a mouse model of cuprizone-induced demyelination.

Experimental neurology·2026

Acute spinal cord injury-acquired pneumonia induces sustained lung injury in mice.

Experimental neurology·2026

Let-7d-5p improves mouse cognitive function by targeting bach1 in Alzheimer's disease.

Experimental neurology·2026

Absence of thyroid hormone transporters Mct8/Oatp1c1 causes distinct spinal cord alterations in adult female mice.

Experimental neurology·2026

Association Between Cognitively Stimulating Activities and Cognitive Function in Older Adults Living in Residential Care Homes.

Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society·2026

The capability approach in rehabilitation: lessons learned from a process evaluation.

Disability and rehabilitation·2026

The impact of self-efficacy on health-related quality of life among community-dwelling older adults with chronic diseases: the mediating role of self-management behaviour.

Frontiers in public health·2026

Advances in rehabilitation for bone and joint pain: a critical narrative review of evidence, gaps, and future directions.

Frontiers in pain research (Lausanne, Switzerland)·2026

Seated anthropometry, functional reach, and hand strength in Korean wheelchair users with spinal cord injury: reference percentiles for assistive-technology and accessible design.

Disability and rehabilitation. Assistive technology·2026

Iterative Development and Usability Evaluation of an Open-Source Rehabilitation Follow-Up Platform: User-Centered Development Study.

JMIR rehabilitation and assistive technologies·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us