Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Elastin is Responsible for Tissue Elasticity

Elastin is Responsible for Tissue Elasticity

Elastic fiber contains the protein elastin along with lesser amounts of other proteins and glycoproteins. The main property of elastin is that it will return to its original shape after being stretched or compressed. Elastic fibers are prominent in elastic tissues found in skin and the elastic ligaments of the vertebral column.
Ligaments and tendons are made of dense regular connective tissue, but in ligaments not all fibers are parallel. Dense regular elastic tissue contains elastin fibers and...

Classification and Mechanical Properties of Synthetic Polymers

Classification and Mechanical Properties of Synthetic Polymers

Synthetic polymers are classified as elastomers, fibers, or plastics based on their crystallinity. Crystallinity, the degree of long-range order in the solid state, influences the mechanical properties (stretching or contracting) of elastomers. Elastomers are flexible polymers that can expand or contract easily upon the application of an external force. They have numerous crosslinks that pull them back into their original shape when stress is removed. Silicones, for instance, are highly elastic...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Proton pump inhibitor co-therapy in patients receiving non-vitamin K antagonist oral anticoagulants: current evidence, gastrointestinal bleeding prevention, and clinical considerations.

Frontiers in cardiovascular medicine·2026

Same author

Hypothalamic POMC neurons regulate intestinal glucose absorption via a gut-brain circuit.

Nature communications·2026

Same author

Distinct age-dependent phenotypes of abnormal liver function tests derived from national Emergency Department data.

Clinical and experimental pediatrics·2026

Same author

OPTIA-AF trial: A randomized study of rhythm-guided antithrombotic strategy after atrial fibrillation ablation in patients with prior drug-eluting stent implantation.

Heart rhythm O2·2026

Same author

Real-World Outcomes of Cryoballoon vs. Radiofrequency Ablation in Atrial Fibrillation: A Multicenter Propensity-Matched Analysis of Short- and Long-term Efficacy.

Korean circulation journal·2026

Same author

Native liver survival and genetic associations in Korean patients with Alagille syndrome.

European journal of pediatrics·2026

Same journal

Corrigendum to "Senescent endothelial cells' response to the degradation of bioresorbable scaffold induces intimal dysfunction accelerating in-stent restenosis" [Acta Biomaterialia 166 (2023) 266-277].

Acta biomaterialia·2026

Same journal

Colorectum and embedded networks of nerve fibers present auxetic responses during uniaxial circumferential extension.

Acta biomaterialia·2026

Same journal

Music-Inspired Acoustic-Piezoelectric Stimulation Accelerates Extracellular Vesicle Production and Programs Therapeutic Function.

Acta biomaterialia·2026

Same journal

Mutant superoxide dismutase 1-catalyzed hydrogen therapy for amyotrophic lateral sclerosis achieved by intercepting oxidative stress-neuroinflammation crosstalk.

Acta biomaterialia·2026

Same journal

Injectable pH-responsive gelatin methacryloyl hydrogel for cuproptosis-synergized sunitinib therapy and immune reprogramming in clear cell renal cell carcinoma.

Acta biomaterialia·2026

Same journal

Corrigendum to "Injectable hydrogel-assisted local lipopolysaccharide delivery improves immune checkpoint blockade therapy" [Acta Biomaterialia 2025, 194, 153-168].

Acta biomaterialia·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 10, 2026

Production of Elastin-like Protein Hydrogels for Encapsulation and Immunostaining of Cells in 3D

Production of Elastin-like Protein Hydrogels for Encapsulation and Immunostaining of Cells in 3D

Published on: May 19, 2018

Resilin: protein-based elastomeric biomaterials.

Renay S-C Su¹, Yeji Kim¹, Julie C Liu²

¹School of Chemical Engineering, Purdue University, West Lafayette, IN 47907-2100, USA.

Acta Biomaterialia

|July 9, 2013

Summary

This summary is machine-generated.

Resilin, an insect protein, offers unique mechanical properties for biomaterials. Protein engineering expands its use in tissue engineering and drug delivery by tuning mechanical and biological functions.

Keywords:

Protein engineering Resilience Self-assembly Thermal responsiveness Tissue engineering

More Related Videos

Thin Film Composite Silicon Elastomers for Cell Culture and Skin Applications: Manufacturing and Characterization

Thin Film Composite Silicon Elastomers for Cell Culture and Skin Applications: Manufacturing and Characterization

Published on: July 3, 2018

Synthesis of Biocompatible Liquid Crystal Elastomer Foams as Cell Scaffolds for 3D Spatial Cell Cultures

Synthesis of Biocompatible Liquid Crystal Elastomer Foams as Cell Scaffolds for 3D Spatial Cell Cultures

Published on: April 11, 2017

Related Experiment Videos

Last Updated: May 10, 2026

Production of Elastin-like Protein Hydrogels for Encapsulation and Immunostaining of Cells in 3D

Production of Elastin-like Protein Hydrogels for Encapsulation and Immunostaining of Cells in 3D

Published on: May 19, 2018

Thin Film Composite Silicon Elastomers for Cell Culture and Skin Applications: Manufacturing and Characterization

Thin Film Composite Silicon Elastomers for Cell Culture and Skin Applications: Manufacturing and Characterization

Published on: July 3, 2018

Synthesis of Biocompatible Liquid Crystal Elastomer Foams as Cell Scaffolds for 3D Spatial Cell Cultures

Synthesis of Biocompatible Liquid Crystal Elastomer Foams as Cell Scaffolds for 3D Spatial Cell Cultures

Published on: April 11, 2017

Area of Science:

Biomaterials Science
Protein Engineering
Tissue Engineering

Background:

Resilin is a natural elastomeric protein in insect cuticles known for high strain, low stiffness, and high resilience.
Resilin-based proteins, derived via molecular cloning, exhibit superior mechanical properties, autofluorescence, self-assembly, and temperature-responsive phase transitions.
These properties suggest applications in biosensors, environmentally responsive materials, tissue engineering, and drug delivery.

Purpose of the Study:

To explore the potential of resilin-based proteins in advanced biomaterial applications.
To investigate how protein engineering can enhance the functionality of resilin-based materials.
To expand the utility of resilin-based biomaterials by incorporating bioactive domains.

Main Methods:

Utilizing molecular cloning techniques to construct resilin-based proteins.
Designing novel proteins by integrating resilin sequences with bioactive domains (e.g., cell-adhesion, matrix metalloproteinase).
Characterizing the mechanical, physical, and biological properties of engineered resilin-based biomaterials.

Main Results:

Engineered resilin-based proteins retain the inherent superior mechanical and physical properties of natural resilin.
Incorporation of bioactive domains allows for control over cellular responses.
Tunable mechanical and biological properties enable diverse applications in tissue engineering.

Conclusions:

Resilin-based biomaterials offer a versatile platform for developing advanced functional materials.
Protein engineering provides a powerful approach to tailor resilin-based materials for specific biomedical applications.
These engineered biomaterials hold significant promise for regenerative medicine, including applications in muscle, vocal fold, cardiovascular, and cartilage tissue engineering.