Related Experiment Video
Updated: May 9, 2026

Estimation of Urinary Nanocrystals in Humans using Calcium Fluorophore Labeling and Nanoparticle Tracking Analysis
Published on: February 9, 2021
A new compound in kidney stones? Powder X-ray diffraction study of calcium glycinate trihydrate
Armel Le Bail1, Michel Daudon, Dominique Bazin
1Institut des Molécules et des Matériaux du Mans, CNRS UMR 6283, Université du Maine, 72085 Le Mans, France. armel.le_bail@univ-lemans.fr
Abstract:
The present identification of a new compound in kidney stones is relevant in clinical practice. Here, poly[[di-μ-aqua-bis(glycinato-κ(2)N,O)calcium(II)] monohydrate], {[Ca(C2H4NO2)2(H2O)2]·H2O}n, has been identified in a possible kidney concretion, although it could be a 'false calculus' associated with Munchausen syndrome. The crystal packing is characterized by an infinite zigzag chain of Ca atoms in [Ca(OW)4O2N2] (OW is a water O atom) square antiprisms, sharing edges formed by water molecules. An uncoordinated water molecule interconnects the parallel chains in a three-dimensional hydrogen-bonding scheme. Similarities between the trihydrate and the monohydrate are described.
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