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Related Concept Videos

Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
Chronic Kidney Disease IV: Nursing Management01:18

Chronic Kidney Disease IV: Nursing Management

Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care​.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of fluid...
Diabetic Nephropathy01:28

Diabetic Nephropathy

Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration occur due to afferent arteriolar...

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Updated: May 9, 2026

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
05:34

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

[Chronic kidney dysfunction in the elderly patient: physiological process or disease?].

Sara Mascia, Roberto Minutolo, Ferdinando Carlo Sasso

    Giornale Italiano Di Nefrologia : Organo Ufficiale Della Societa Italiana Di Nefrologia
    |July 9, 2013
    PubMed
    Summary

    The number of older adults diagnosed with chronic kidney disease (CKD) is increasing. Further research is needed to understand CKD in the elderly and improve their care.

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    Assessment of Vascular Function in Patients With Chronic Kidney Disease
    08:50

    Assessment of Vascular Function in Patients With Chronic Kidney Disease

    Published on: June 16, 2014

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    5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
    05:34

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    Published on: April 4, 2025

    Assessment of Vascular Function in Patients With Chronic Kidney Disease
    08:50

    Assessment of Vascular Function in Patients With Chronic Kidney Disease

    Published on: June 16, 2014

    Area of Science:

    • Nephrology
    • Geriatrics
    • Internal Medicine

    Context:

    • Rising prevalence of chronic kidney disease (CKD) in elderly populations.
    • Increased referrals of geriatric patients with CKD to renal clinics.
    • Establishment of Geriatric Nephrology as a dedicated study group by the American Society of Nephrology.

    Purpose:

    • To increase knowledge regarding chronic kidney disease (CKD) in older patients.
    • To improve the clinical management of elderly individuals with CKD.
    • To evaluate recent studies on the relationship between aging and CKD.

    Summary:

    • Most new chronic kidney disease (CKD) diagnoses occur in individuals aged 65 and older, often with mild-to-moderate disease.
    • There is a need to clarify diagnostic criteria for 'true' CKD in the elderly.
    • Further investigation is required to understand the clinical implications of CKD in older adults.

    Impact:

    • Enhancing understanding of age-related kidney disease.
    • Guiding clinical practice for geriatric nephrology.
    • Informing future research directions in elderly CKD management.