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Stress: Neurobiology, consequences and management
Anil Kumar1, Puneet Rinwa, Gurleen Kaur
1Department of Pharmacology, University Institute of Pharmaceutical Sciences, UGC Centre of Advanced Study, Panjab University, Chandigarh, India.
Neuroresearch increasingly focuses on stress, utilizing animal models to study stress-induced pathologies and their management. This review covers stress neurobiology, neurotransmitter impacts, and effective pharmacological and non-pharmacological treatments.
Area of Science:
- Neuroscience
- Psychiatry
- Pharmacology
Background:
- Stress, encompassing physical and psychological factors, is a growing area of neuroresearch.
- Recent decades show increased interest in stress-induced manifestations, leading to better animal models for stress pathologies.
- Dysregulation of the stress system can disrupt growth and development, potentially causing psychiatric disorders.
Purpose of the Study:
- To review the neurobiology of different stress types and affected neurotransmitters.
- To discuss complications of stress and their management strategies.
- To highlight the impact of stress on animal models for understanding stress mechanisms and management.
Main Methods:
- Review of existing literature on stress neurobiology.
- Analysis of animal models for inducing and studying stress.
- Examination of pharmacological and non-pharmacological stress management techniques.
Main Results:
- Stress impacts neurobiology, affecting neurotransmitter systems.
- Animal models provide insights into stress-induced behavioral changes and pathologies.
- Both pharmacological and non-pharmacological interventions, including herbal remedies, yoga, and meditation, show effectiveness.
Conclusions:
- Understanding stress neurobiology is crucial for managing stress-related disorders.
- Animal models are valuable tools for investigating stress mechanisms.
- Safe and effective management of stress involves diverse approaches, with non-pharmacological methods gaining popularity.
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