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Effects of topical sprays on allergy-induced nasal obstruction in children

Mehmet Yaşar1, Ismail Önder Uysal, Emine Elif Altuntaş

  • 1Department of Otolaryngology, Kayseri Training and Research Hospital, 38010 Kayseri, Turkey. drmyasar@hotmail.com

Kulak Burun Bogaz Ihtisas Dergisi : KBB = Journal of Ear, Nose, and Throat
|July 10, 2013
PubMed

Insights

Mometasone furoate and azelastine nasal sprays effectively reduce nasal congestion and improve nasal cavity volume in children with allergic rhinitis, outperforming isotonic sea water spray.

Area of Science:

  • Pediatric Allergy and Immunology
  • Otolaryngology
  • Pharmacology

Background:

  • Allergic rhinitis frequently causes nasal obstruction in children.
  • Effective management of nasal congestion is crucial for improving quality of life.

Purpose of the Study:

  • To compare the efficacy of mometasone furoate nasal spray, azelastine nasal spray, and isotonic sea water nasal spray.
  • To evaluate their impact on nasal obstruction in pediatric patients.

Main Methods:

  • A randomized study involving 60 children (7-16 years) with allergic rhinitis.
  • Assessment of nasal passage volume using acoustic rhinometry.
  • Comparison of treatments: azelastine, mometasone furoate, and isotonic sea water.

Main Results:

  • Both azelastine and mometasone furoate significantly reduced nasal congestion.
  • These active treatments led to a greater increase in nasal cavity volume compared to isotonic sea water.

Conclusions:

  • Mometasone furoate and azelastine are effective treatments for allergic rhinitis in children.
  • These agents successfully decrease nasal congestion and enhance nasal volume.
Abstract

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