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Serendipitous recanalization of basilar artery occlusion
Jeffrey A Switzer1, Scott E Forseen, Askiel Bruno
1Department of Neurology, Georgia Regents University, Augusta, GA.
Objective:
To describe a case of recanalization of a basilar artery occlusion with intravenous (IV) tenecteplase.
Case:
A 74-year-old man with a history of cardiomyopathy presented to an outside hospital with acute vertigo, dysarthria, gaze deviation, and ataxia. Computerized tomography arteriography demonstrated occlusion of the proximal basilar artery. IV tissue plasminogen activator was ordered; however, the patient received a cardiac dose of IV tenecteplase. The patient was transferred to our facility, whereby symptoms resolved, and repeat computerized tomography arteriography displayed recanalization of the basilar artery.
Conclusions:
Tenecteplase has enhanced biochemical and pharmacokinetic properties that may be ideal for treatment of basilar artery occlusion and should be further investigated in a randomized clinical trial.
