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Updated: May 9, 2026

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

Published on: December 28, 2017

[Developments in radiotherapy: image-guided and minimally invasive].

Marco van Vulpen¹, Maurice A A J van den Bosch, H M Lenny Verkooijen

¹Universitair Medisch Centrum Utrecht, divisie Beeld, Utrecht, the Netherlands. m.vanvulpen@umcutrecht.nl

Nederlands Tijdschrift Voor Geneeskunde

|July 10, 2013

Summary

Modern radiotherapy uses advanced imaging for precise cancer treatment, reducing side effects and enabling fewer, more effective radiation fractions for patients.

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Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

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Area of Science:

Oncology
Medical Physics
Radiology

Background:

Radiotherapy, a cornerstone cancer treatment, is evolving from imprecise methods to high-precision therapies.
Historically, radiotherapy often caused unpreventable side effects due to its imprecise nature.
Advancements in imaging and techniques are transforming radiation oncology.

Purpose of the Study:

To highlight the evolution of radiotherapy towards a high-precision treatment modality.
To explain how improved imaging enhances tumor targeting and minimizes damage to healthy tissues.
To demonstrate the benefits of modern radiotherapy techniques for patient outcomes.

Main Methods:

Utilizing improved imaging quality for accurate tumor localization in space and time.
Integrating anatomical and functional information for precise treatment planning.
Employing advanced techniques for enhanced guidance of radiation delivery during treatment.

Main Results:

Radiotherapy has become a high-precision therapy comparable to surgery.
Reduced radiotherapy margins and decreased radiation dose to normal tissues achieved.
Enabling fewer, highly effective radiation fractions for various cancer indications.

Conclusions:

Modern radiotherapy offers a less toxic and more effective treatment strategy.
Advanced imaging and techniques significantly improve treatment precision and patient benefit.
The shift towards precision radiotherapy enhances curative potential while minimizing side effects.