Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Nursing Assessment of the Genitourinary System II: Inspection and Palpation01:26

Nursing Assessment of the Genitourinary System II: Inspection and Palpation

The nursing assessment of the genitourinary (GU) system involves a systematic inspection and palpation to identify abnormalities in the kidneys, bladder, and surrounding structures.InspectionMouth: Inspect for signs of kidney dysfunction, such as stomatitis (inflammation of the mouth) and ammonia breath, which may occur in advanced kidney disease due to the buildup of urea, breaking down into ammonia.Skin: Check for pallor, which could indicate anemia caused by kidney disease. Look for...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Construct validity, reliability, and sensitivity of proxy-reported pain interference in individuals with cerebral palsy.

The journal of pain·2026
Same author

The feasibility of a subgroup approach to create sensory-motor behavioral response profiles from a modified quantitative sensory test in cerebral palsy.

Pain·2025
Same author

Reliability of Actigraphy for the Assessment of Sleep and Circadian Rhythms in Rett and Related Syndromes.

Journal of intellectual disability research : JIDR·2025
Same author

Educational outcomes of a cohort of children with autism who received early intensive behavioral intervention.

The Journal of special education·2025
Same author

Psychological Predictors of Pain Outcomes in Children With Cerebral Palsy Undergoing Orthopaedic Surgery.

Journal of pediatric orthopedics·2025
Same author

Introduction to the Special Issue on Phenotypic Explorations of Phelan McDermid Syndrome and Other Developmental Synaptopathies.

American journal on intellectual and developmental disabilities·2025

Related Experiment Video

Updated: May 9, 2026

Investigating Pain-Related Avoidance Behavior using a Robotic Arm-Reaching Paradigm
09:00

Investigating Pain-Related Avoidance Behavior using a Robotic Arm-Reaching Paradigm

Published on: October 3, 2020

Parent-reported pain in Rett syndrome.

Frank J Symons1, Breanne Byiers, Raymond C Tervo

  • 1Department of Educational Psychology, University of Minnesota, Minneapolis, MN 55455, USA. symon007@umn.edu

The Clinical Journal of Pain
|July 10, 2013
PubMed
Summary
This summary is machine-generated.

Pain is a significant issue for individuals with Rett syndrome (RTT), with nearly a quarter experiencing chronic pain. Facial expressions and vocalizations are key pain indicators, often linked to gastro-intestinal problems.

More Related Videos

Regenerative Peripheral Nerve Interface: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain
03:53

Regenerative Peripheral Nerve Interface: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain

Published on: March 15, 2024

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
07:12

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats

Published on: January 21, 2020

Related Experiment Videos

Last Updated: May 9, 2026

Investigating Pain-Related Avoidance Behavior using a Robotic Arm-Reaching Paradigm
09:00

Investigating Pain-Related Avoidance Behavior using a Robotic Arm-Reaching Paradigm

Published on: October 3, 2020

Regenerative Peripheral Nerve Interface: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain
03:53

Regenerative Peripheral Nerve Interface: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain

Published on: March 15, 2024

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
07:12

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats

Published on: January 21, 2020

Area of Science:

  • Neurology
  • Pediatrics
  • Pain Management

Background:

  • Rett syndrome (RTT) is a neurodevelopmental disorder characterized by severe motor and communication impairments.
  • Patients with RTT often have chronic health issues, increasing the risk of unrecognized pain.
  • Accurate pain assessment is challenging due to communication difficulties in RTT.

Purpose of the Study:

  • To investigate the frequency, communication methods, and sources of pain in individuals with Rett syndrome.
  • To provide preliminary data on the prevalence and characteristics of pain in this population.

Main Methods:

  • A health survey was administered to caregivers of 44 clinically diagnosed RTT patients.
  • The survey included items from the Non-Communicating Children's Pain Checklist - Revised to assess pain.
  • Data collected included pain frequency, communication methods, and pain sources.

Main Results:

  • 24% of surveyed individuals with RTT experienced pain on 8 or more days in the prior month.
  • Facial expressions (85%) and vocalizations (82%) were the most common pain communication methods.
  • Gastro-intestinal issues were the most frequently reported pain source (66%).

Conclusions:

  • Pain is a prevalent issue for a significant subgroup of individuals with Rett syndrome.
  • The findings highlight the need for increased awareness and improved pain recognition in RTT patients.
  • The complex health and communication challenges in RTT necessitate careful pain assessment strategies.