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Paramagnetic Relaxation Enhancement for Detecting and Characterizing Self-Associations of Intrinsically Disordered Proteins
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Paramagnetic Relaxation Enhancement for Detecting and Characterizing Self-Associations of Intrinsically Disordered Proteins

Published on: September 23, 2021

Studying the structure and dynamics of biomolecules by using soluble paramagnetic probes

Henry G Hocking1, Klaus Zangger, Tobias Madl

  • 1Chair of Biomolecular NMR, Department Chemie, Technische Universität München, 85747 Garching (Germany); Institute of Structural Biology, Helmholtz Zentrum München, 85764 Neuherberg (Germany).

Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry
|July 10, 2013
PubMed
Summary

Nuclear Magnetic Resonance (NMR) spectroscopy struggles with large biomolecules. Solvent paramagnetic relaxation enhancements (PREs) offer a powerful new method to study their structure and dynamics.

Keywords:
NMR spectroscopymagnetic propertiesproteinssolvent effectsstructural biology

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