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Related Experiment Video

Updated: May 9, 2026

Paradigms of Lower Extremity Electrical Stimulation Training After Spinal Cord Injury
08:07

Paradigms of Lower Extremity Electrical Stimulation Training After Spinal Cord Injury

Published on: February 1, 2018

Patient-perceived differences between constant current and constant voltage spinal cord stimulation systems.

Stephanie Washburn1, Roger Catlin, Klee Bethel

  • 1St. Jude Medical, Plano, TX, USA.

Neuromodulation : Journal of the International Neuromodulation Society
|July 11, 2013
PubMed
Summary

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Patients with chronic pain preferred constant current (CC) spinal cord stimulation (SCS) over constant voltage (CV) systems, reporting better pain relief and satisfaction. This suggests CC systems may be a superior choice for SCS therapy.

Area of Science:

  • Neuromodulation
  • Pain Management
  • Biomedical Engineering

Background:

  • Spinal cord stimulation (SCS) uses implantable pulse generators with either constant current (CC) or constant voltage (CV) power sources.
  • CC systems maintain consistent current delivery by adjusting voltage based on impedance, while CV systems deliver variable current with changing impedance.
  • Both SCS systems manage chronic pain via paresthesia, but patient preference leans towards CC stimulation.

Purpose of the Study:

  • To compare patient preference and stimulation sensation between CC and CV neurostimulation systems.
  • To evaluate the impact of CC versus CV stimulation on pain relief, satisfaction, and quality of life.

Main Methods:

  • A randomized, double-blinded crossover study involving 30 patients undergoing SCS.
Keywords:
Chronic painconstant currentconstant voltageneurostimulationspinal cord stimulation

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Last Updated: May 9, 2026

Paradigms of Lower Extremity Electrical Stimulation Training After Spinal Cord Injury
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Paradigms of Lower Extremity Electrical Stimulation Training After Spinal Cord Injury

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Dorsal Column Steerability with Dual Parallel Leads using Dedicated Power Sources: A Computational Model

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  • Patients were implanted with a trial system and then randomized to receive either CC or CV stimulation, followed by crossover to the alternate system.
  • Evaluations included patient well-being, pain relief, satisfaction, quality of life, preference, and stimulation sensation, analyzed using statistical tests like Z-test and paired t-test.
  • Main Results:

    • A majority of patients (70%) preferred CC stimulation over CV stimulation (30%).
    • CC stimulation resulted in a significantly greater reduction in pain scores compared to CV stimulation.
    • Patients initially receiving CC stimulation were less likely to be satisfied with subsequent CV stimulation.

    Conclusions:

    • Patients preferred CC systems and reported greater satisfaction and pain relief during the SCS trial period.
    • The observed short-term benefits of CC systems warrant consideration when selecting an SCS device.
    • Further research is needed to compare long-term outcomes between CC and CV systems.