Related Experiment Videos
[Hemodynamic changes in varicoceles and their relation to fertility]
E Malatinský1, R Zajac, P Lepies
1Urologického oddelenia FN, Bratislava.
Bratislavske Lekarske Listy
|May 1, 1990
Summary
Varicocele is linked to infertility. This study found significant hemodynamic changes in the testicular vascular system of sterile men, suggesting a direct impact on sperm production.
Area of Science:
- Urology
- Andrology
- Vascular Medicine
Background:
- Varicocele, an enlargement of veins within the scrotum, is frequently associated with male infertility.
- Understanding the vascular pathophysiology of varicocele is crucial for addressing its impact on spermatogenesis.
Purpose of the Study:
- To investigate and characterize hemodynamic alterations in the testicular vascular bed of patients with varicocele.
- To determine the correlation between observed vascular changes and infertility in varicocele patients.
Main Methods:
- Modified abdominal angiography was employed to examine the vascular system of the testes.
- The study included 45 sterile patients and 6 fertile patients diagnosed with varicocele.
Main Results:
- Persistence of contrast medium in the left internal testicular artery was noted in 5 sterile patients.
- Venous reflux from the left renal vein into the left internal testicular vein was the most common finding, present in 45 sterile and 2 fertile patients.
- Pathologic vessel openings or origins were observed in some sterile individuals.
Conclusions:
- A significantly higher incidence of hemodynamic changes was observed in sterile varicocele patients compared to fertile ones.
- These vascular abnormalities strongly suggest a direct relationship between hemodynamic changes and impaired spermiogenesis in varicocele.