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Stewart-Treves syndrome: a case report
1Memorial Sloan-Kettering Cancer Center, 1,275 York Avenue, Suite A342, New York, NY 10065, USA. mckeownd@mskcc.org
Annals of the Royal College of Surgeons of England
|July 11, 2013
Summary
Chronic lymphoedema can progress to Stewart-Treves syndrome, a rare cancer, after mastectomy. Early detection through regular follow-ups is crucial for managing this severe complication.
Area of Science:
- Oncology
- Dermatology
- Surgical Oncology
Background:
- Stewart-Treves syndrome is a rare condition characterized by angiosarcoma developing in the setting of chronic lymphoedema.
- Chronic lymphoedema is a potential long-term complication following breast cancer surgery, particularly modified radical mastectomy with lymph node dissection.
Observation:
- A 63-year-old woman with a history of modified radical mastectomy, lymph node dissection, chemotherapy, and radiotherapy developed chronic lymphoedema.
- The patient subsequently developed cutaneous lesions indicative of Stewart-Treves syndrome.
Findings:
- Chemotherapy initially stabilized cutaneous lesions but did not prevent angiosarcoma metastasis.
- The patient ultimately succumbed to the disease, highlighting the aggressive nature of Stewart-Treves syndrome.
Implications:
- Vigilance and regular patient follow-up are essential after mastectomy and lymphoedema diagnosis.
- Early identification and intervention strategies for Stewart-Treves syndrome in at-risk populations are critical.
- This case underscores the importance of monitoring chronic lymphoedema for potential malignant transformation.
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