Related Experiment Video

Updated: May 9, 2026

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
08:52

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice

Published on: February 22, 2019

Bordetella parapertussis bacteremia: two case reports

Rebecca Wallihan1, Rangaraj Selvarangan, Mario Marcon

  • 1Section of Infectious Diseases, Nationwide Children's Hospital, Columbus, OH 43205, USA. rebecca.wallihan@nationwidechildrens.org

The Pediatric Infectious Disease Journal
|July 11, 2013
PubMed

Insights

Bordetella parapertussis rarely causes invasive disease. This study details two pediatric cases of B. parapertussis bacteremia, highlighting clinical presentation and diagnostic methods.

Area of Science:

  • Pediatric infectious diseases
  • Bacteriology
  • Respiratory infections

Background:

  • Bordetella parapertussis is a known cause of pertussis-like illness in children.
  • Invasive infections due to B. parapertussis are infrequently reported in medical literature.
  • Understanding the spectrum of B. parapertussis infections is crucial for accurate diagnosis and management.

Observation:

  • Two pediatric patients presented with B. parapertussis bacteremia.
  • The clinical presentation of these invasive cases was documented.
  • Methods for isolating B. parapertussis from blood cultures were employed.

Findings:

  • B. parapertussis can lead to invasive bloodstream infections in children, although rare.
  • Successful isolation techniques for B. parapertussis from clinical specimens were utilized.
  • The study contributes to the limited data on invasive B. parapertussis infections.

Implications:

  • Clinicians should consider B. parapertussis in the differential diagnosis of severe respiratory and systemic infections in children.
  • Enhanced diagnostic approaches may be needed to identify invasive B. parapertussis.
  • Further research is warranted to understand the epidemiology and clinical characteristics of invasive B. parapertussis infections.

More Related Videos

A Precise Pathogen Delivery and Recovery System for Murine Models of Secondary Bacterial Pneumonia13:45

A Precise Pathogen Delivery and Recovery System for Murine Models of Secondary Bacterial Pneumonia

Published on: September 21, 2019

Related Concept Videos

Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Pneumonia I: Introduction01:29

Pneumonia I: Introduction

Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

The pathophysiology of pneumonia involves the following steps: