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Properties of mannitol injection (25%) after repeated autoclavings
Abstract:
The physical and chemical properties of mannitol injection 25% were examined after repeated autoclavings. The product was found to be stable after five autoclavings of 250 F for 15 minutes each. No extracts from the rubber closures were found. It is advised that the product may be repeatedly heated or autoclaved if crystals appear as a result of storage.