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Updated: Sep 2, 2026

Quantitation of Protein Expression and Co-localization Using Multiplexed Immuno-histochemical Staining and Multispectral Imaging
Published on: April 8, 2016
[Comparative study on clinical staging and histological grading of prostatic adenocarcinoma between Chinese and
1Department of Pathology, Third Teaching Hospital, Norman Bethune University of Medical Sciences.
Abstract:
A comparative study on prostatic adenocarcinomas in 111 cases of Chinese and in 460 cases of Japanese was conducted. The results revealed that the average age of patients was 65.5 years in the Chinese group with a peak age between 65-69 years; while in the Japanese group, the average age was 71.7 years with a peak age between 70-74 years. 79.3% of the Chinese patients were at B and C stages according to clinical staging during the primary operation, while in the Japanese patients, 52.0% were at D stage (P less than 0.001). Histological grading in the Chinese patients revealed that 61.3% of the tumors were poorly differentiated, while in the Japanese group, 51.1% of the tumors were moderately differentiated (P less than 0.001). The reasons of this difference are discussed.
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