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Updated: May 9, 2026

Germ Cell Transplantation and Testis Tissue Xenografting in Mice
Published on: February 6, 2012
Late relapse of testis cancer
Yaron Ehrlich1, Eli Rosenbaum, Jack Baniel
1Department of Urology and Oncology, Rabin Medical Center, Petach Tikva, 49100, Israel, yaronehrlich@gmail.com.
Abstract:
Most relapses of germ-cell tumors occur within 2 years of initial treatment. In 2 % to 4 % of patients, relapse may occur later. The retroperitoneum is the primary site of late relapses, and alpha-fetoprotein is the predominant marker. These tumors are highly resistant to chemotherapy. Surgical resection is the preferred treatment. If the recurrent disease is inoperable, salvage chemotherapy may be instituted, followed by resection of the residual disease.
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