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Functional probe for annulus fibrosus-targeted intervertebral disc degeneration imaging

Hye-Yeong Kim1, Michael Mcclincy, Nam V Vo

  • 1University of Pittsburgh, Department of Radiology, School of Medicine, Molecular Imaging Laboratory, Pittsburgh, Pennsylvania 15219, USA.

Journal of Biomedical Optics
|July 11, 2013
PubMed
Summary

A new fluorescent probe, HYK52, effectively labels intervertebral disc tissue for early diagnosis of intervertebral disc degeneration (IDD). This probe shows low toxicity and potential for multimodal imaging, aiding in low back pain management.

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