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Updated: May 9, 2026
08:01
Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines
Published on: April 21, 2022
Primary pericardial mesothelioma: a rare entity.
Mohit Godar1, Jianhua Liu, Pengguo Zhang
1Department of Radiology, Norman Bethune College of Medicine, The Second Hospital of Jilin University, 218 Ziqiang Street, Nanguan District, Changchun, Jilin 130041, China.
Case Reports in Oncological Medicine
|July 11, 2013
Summary
Primary pericardial malignant mesothelioma is a rare cancer. This case study highlights a patient
Area of Science:
- Oncology
- Pathology
Background:
- Primary pericardial malignant mesothelioma is an exceptionally rare cancer originating from the pericardial mesothelial cells.
- Clinical presentation is often nonspecific, leading to diagnosis post-surgery or autopsy.
- This aggressive neoplasm has a poor prognosis, with survival typically under six months.
Purpose of the Study:
- To present a case study of a patient diagnosed with primary pericardial malignant mesothelioma.
- To discuss the diagnostic process and treatment challenges for this rare condition.
Main Methods:
- Radiologic evaluation including imaging of the pericardium and pleural spaces.
- Histological and immunohistochemical analysis of surgical specimens for definitive diagnosis.
- Surgical intervention as the primary therapeutic approach for localized disease.
Main Results:
- A 68-year-old patient presented with a small pericardial nodule, pericardial, and bilateral pleural effusions.
- Diagnosis was confirmed via post-operative histological and immunohistochemical examination.
- The patient achieved a 24-month disease-free survival post-surgery, but succumbed to rapid local recurrence at 27 months.
Conclusions:
- Radical surgery is the primary treatment for localized primary pericardial malignant mesothelioma.
- Despite initial success, rapid recurrence underscores the aggressive nature and poor prognosis of this rare cancer.
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