Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Structural Isomerism02:34

Structural Isomerism

Isomerism in Complexes
Isomers are different chemical species that have the same chemical formula. Structural isomerism of coordination compounds can be divided into two subcategories, the linkage isomers and coordination-sphere isomers.
Linkage isomers occur when the coordination compound contains a ligand that can bind to the transition metal center through two different atoms. For example, the CN− ligand can bind through the carbon atom or through the nitrogen atom. Similarly, SCN− can be...
Valence Bond Theory02:42

Valence Bond Theory

Coordination compounds and complexes exhibit different colors, geometries, and magnetic behavior, depending on the metal atom/ion and ligands from which they are composed. In an attempt to explain the bonding and structure of coordination complexes, Linus Pauling proposed the valence bond theory, or VBT, using the concepts of hybridization and the overlapping of the atomic orbitals. According to VBT, the central metal atom or ion (Lewis acid) hybridizes to provide empty orbitals of suitable...
Acid Halides to Alcohols: LiAlH4 Reduction01:19

Acid Halides to Alcohols: LiAlH4 Reduction

Acid halides are reduced to alcohols in the presence of a strong reducing agent like lithium aluminum hydride.
The mechanism proceeds in three steps. First, the nucleophilic hydride ion attacks the carbonyl carbon of the acid halide to form a tetrahedral intermediate. Next, the carbonyl group is re-formed, and the halide ion departs as a leaving group, generating an aldehyde. A second nucleophilic attack by the hydride yields an alkoxide ion, which, upon protonation, gives a primary alcohol as...
Complexation Equilibria: Factors Influencing Stability of Complexes01:09

Complexation Equilibria: Factors Influencing Stability of Complexes

In complexation reactions, metal cations are the electron pair acceptors, and the ligands are the electron pair donors. The stability of the metal complexes depends primarily on the complexing ability of the central metal ion and the nature of the ligands. Generally, the complexing ability of the metal ion depends on the size and charge of the ion. As the metal ion size increases, the stability of the metal complexes decreases, provided that the valency of the metal ion and the ligands remain...
Hydroboration-Oxidation of Alkenes03:08

Hydroboration-Oxidation of Alkenes

In addition to the oxymercuration–demercuration method, which converts the alkenes to alcohols with Markovnikov orientation, a complementary hydroboration-oxidation method yields the anti-Markovnikov product. The hydroboration reaction, discovered in 1959 by H.C. Brown, involves the addition of a B–H bond of borane to an alkene giving an organoborane intermediate. The oxidation of this intermediate with basic hydrogen peroxide forms an alcohol.
Radical Substitution: Allylic Bromination01:27

Radical Substitution: Allylic Bromination

In organic synthesis, the formation of products can be altered by changing the reaction conditions. For example, a dibromo addition product is formed when propene is treated with bromine at room temperature. In contrast, propene undergoes allylic substitution in non-polar solvents at high temperatures to give 3-bromopropene. In order to avoid the addition reaction, the bromine concentration must be kept as low as possible throughout the reaction. This can be achieved using N-bromosuccinimide...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Identifying Reactivity Differences of Two-Carbon-Atom-Based Legacy Refrigerants at Group 9 Metal Pincer Complexes.

ACS organic & inorganic Au·2025
Same author

Activation and Functionalization of Organic Disulfides by Bis(Perfluoroalkyl) Complexes of Nickel(II).

Organometallics·2025
Same author

Nickel Perfluoroalkyl Complexes Supported by Simple Acetate Coligands.

Organometallics·2024
Same author

Scrutinizing formally Ni<sup>IV</sup> centers through the lenses of core spectroscopy, molecular orbital theory, and valence bond theory.

Chemical science·2023
Same author

Synthesis, structure, and electrochemical properties of [LNi(R<sub>f</sub>)(C<sub>4</sub>F<sub>8</sub>)]<sup>-</sup> and [LNi(R<sub>f</sub>)<sub>3</sub>]<sup>-</sup> complexes.

Dalton transactions (Cambridge, England : 2003)·2022
Same author

Solvated Nickel Complexes as Stoichiometric and Catalytic Perfluoroalkylation Agents*.

Angewandte Chemie (International ed. in English)·2021

Related Experiment Video

Updated: May 9, 2026

Characterization of Electrode Materials for Lithium Ion and Sodium Ion Batteries Using Synchrotron Radiation Techniques
10:03

Characterization of Electrode Materials for Lithium Ion and Sodium Ion Batteries Using Synchrotron Radiation Techniques

Published on: November 11, 2013

Lithium bromide-induced structural changes in a nickel bis-alkoxide complex.

Hiromi Ichiokai1, David A Vicic

  • 1Department of Chemistry, University of Hawaii, 2545 McCarthy Mall, Honolulu, HI 96822, USA.

Acta Chimica Slovenica
|July 12, 2013
PubMed
Summary

A new nickel complex, bis-alkoxide [(DEAMP)2Ni], reacts with lithium bromide to form a chiral-at-metal adduct. This five-coordinate nickel complex features chiral nickel and oxygen atoms, with one diastereomer precipitating from solution.

More Related Videos

Effect of Microwave Synthesis Conditions on the Structure of Nickel Hydroxide Nanosheets
07:57

Effect of Microwave Synthesis Conditions on the Structure of Nickel Hydroxide Nanosheets

Published on: August 18, 2023

In Situ Neutron Powder Diffraction Using Custom-made Lithium-ion Batteries
11:25

In Situ Neutron Powder Diffraction Using Custom-made Lithium-ion Batteries

Published on: November 10, 2014

Related Experiment Videos

Last Updated: May 9, 2026

Characterization of Electrode Materials for Lithium Ion and Sodium Ion Batteries Using Synchrotron Radiation Techniques
10:03

Characterization of Electrode Materials for Lithium Ion and Sodium Ion Batteries Using Synchrotron Radiation Techniques

Published on: November 11, 2013

Effect of Microwave Synthesis Conditions on the Structure of Nickel Hydroxide Nanosheets
07:57

Effect of Microwave Synthesis Conditions on the Structure of Nickel Hydroxide Nanosheets

Published on: August 18, 2023

In Situ Neutron Powder Diffraction Using Custom-made Lithium-ion Batteries
11:25

In Situ Neutron Powder Diffraction Using Custom-made Lithium-ion Batteries

Published on: November 10, 2014

Area of Science:

  • Organometallic Chemistry
  • Coordination Chemistry
  • Chiral Synthesis

Background:

  • The synthesis and characterization of novel metal complexes are crucial for advancing catalysis and materials science.
  • Chiral-at-metal complexes offer unique properties for asymmetric synthesis and stereoselective reactions.
  • Nickel-alkoxide complexes are versatile precursors in organometallic chemistry.

Purpose of the Study:

  • To synthesize and characterize a novel bis-alkoxide nickel complex.
  • To investigate the reaction of the nickel complex with lithium bromide.
  • To explore the formation of chiral-at-metal complexes and their structural features.

Main Methods:

  • Synthesis of the bis-alkoxide nickel complex [(DEAMP)2Ni].
  • Reaction of the nickel complex with trace amounts of lithium bromide.
  • Crystallization and characterization of the resulting bis-LiBr adduct.

Main Results:

  • The bis-alkoxide [(DEAMP)2Ni] reacted with lithium bromide to form a bis-LiBr adduct (2).
  • The adduct features a chiral-at-metal complex where DEAMP ligand oxygens coordinate to lithium.
  • The new complex is five-coordinate at nickel, with chiral nickel and oxygen atoms; one diastereomer precipitated from pentane.
  • Lithium ions rigidify the solid-state structure by coordinating to oxygen and bromide atoms.

Conclusions:

  • A novel chiral-at-metal nickel-alkoxide complex has been synthesized and characterized.
  • The reaction with lithium bromide leads to the formation of a rigid, five-coordinate nickel complex.
  • The study highlights the potential of such complexes in chiral applications.