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NADPH:O2 oxidoreductase of human eosinophils in the cell-free system
B G Bolscher1, L Koenderman, A T Tool
1Central Laboratory, Netherlands Red Cross Blood Transfusion Service, Amsterdam.
FEBS Letters
|July 30, 1990
Abstract:
The NADPH oxidase of human eosinophils, measured in the cell-free system, shows the same characteristics as the enzyme from human neutrophils. All proteins required for activity of the enzyme are expressed in eosinophils at a higher level than in neutrophils. Eosinophils isolated from patients with chronic granulomatous disease show the same molecular defects as the neutrophils from these patients.