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Related Concept Videos

Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
Export of Mitochondrial and Chloroplast Genes02:19

Export of Mitochondrial and Chloroplast Genes

A eukaryotic cell can have up to three different types of genetic systems: nuclear, mitochondrial, and chloroplast. During evolution, organelles have exported many genes to the nucleus; this transfer is still ongoing in some plant species. Approximately 18% of the Arabidopsis thaliana nuclear genome is thought to be derived from the chloroplast’s cyanobacterial ancestor, and around 75% of the yeast genome derived from the mitochondria’s bacterial ancestor. This export has occurred irrespective...

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Related Experiment Video

Updated: May 9, 2026

Mapping Mammalian 3D Genome Interactions with Micro-C-XL
11:41

Mapping Mammalian 3D Genome Interactions with Micro-C-XL

Published on: November 3, 2023

MIG: Multi-Image Genome viewer.

Simon J McGowan1, Jim R Hughes, Zong-Pei Han

  • 1Computational Biology Research Group and Molecular Haemotology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Headington, Oxford OX3 9DS, UK.

Bioinformatics (Oxford, England)
|July 12, 2013
PubMed
Summary
This summary is machine-generated.

The Multi-Image Genome (MIG) viewer is a web tool for analyzing large genomic datasets. It efficiently visualizes, filters, and exports genome browser data for various applications.

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Published on: December 22, 2017

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Last Updated: May 9, 2026

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Published on: November 3, 2023

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Published on: December 22, 2017

Area of Science:

  • Genomics
  • Bioinformatics
  • Computational Biology

Background:

  • Genome browsers are essential tools for visualizing genomic data.
  • Analyzing large-scale genomic datasets presents significant computational challenges.
  • Existing tools may lack the flexibility to handle diverse data types and large volumes.

Purpose of the Study:

  • To introduce the Multi-Image Genome (MIG) viewer, a novel web-based application.
  • To provide a scalable solution for visualizing and analyzing numerous genome browser regions.
  • To facilitate data querying, filtering, and export for downstream genomic research.

Main Methods:

  • Development of a web-based application for multi-image genome data visualization.
  • Implementation of functionalities for querying and filtering large sets of genome browser regions.
  • Integration of data export options in various standard formats.

Main Results:

  • The MIG viewer enables efficient visualization of thousands of genome browser regions.
  • The application successfully supports the analysis of ChIP-Seq and RNA-Seq data.
  • Somatic mutations in genome resequencing projects can be effectively detected using MIG.

Conclusions:

  • The Multi-Image Genome (MIG) viewer is a versatile tool for genomic data analysis.
  • Its capabilities extend to various applications, including epigenomics and transcriptomics.
  • MIG provides a robust platform for exploring and interpreting complex genomic datasets.