Oxyluciferin photoacidity: the missing element for solving the keto-enol mystery?

Luís Pinto da Silva1, Ron Simkovitch, Dan Huppert

  • 1Centro de Investigação em Química, Departamento de Química e Bioquímica, Faculdade de Ciências da Universidade do Porto, R. Campo Alegre 687, 4169-007 Porto (Portugal), Fax: (+351) 220 402 659.

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Keto–Enol Tautomerism: Mechanism

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Reactivity of Enols

Enols are a class of compounds where a hydroxyl group is attached to a carbon–carbon double bond, which implies that it is a vinyl alcohol. A carbonyl compound with an α hydrogen undergoes keto–enol tautomerism and remains in equilibrium with its tautomer, the enol form. Usually, the keto tautomer is present in a higher concentration than the enol tautomer due to the higher bond energy of C=O compared to C=C. Moreover, the direction of the keto–enol equilibrium is governed by factors like...
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α-Hydroxy Ketones via Reductive Coupling of Esters: Acyloin Condensation Overview

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