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The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
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Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
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Published on: February 14, 2014

Aging, the central nervous system, and mobility.

Andrea L Rosso1, Stephanie A Studenski, Wen G Chen

  • 1Center for Aging and Population Health, Graduate School of Public Health, 130 North Bellefield Street, Room 507, Pittsburgh, PA 15213. rosanoc@edc.pitt.edu.

The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
|July 12, 2013
PubMed
Summary
This summary is machine-generated.

Central nervous system (CNS) changes significantly impact mobility limitations in older adults. Future research should integrate CNS and musculoskeletal factors for better understanding and interventions.

Keywords:
Central nervous systemMobility.Motor control

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Area of Science:

  • Gerontology
  • Neuroscience
  • Biomedical Research

Background:

  • Mobility limitations are prevalent and dangerous in community-dwelling older adults.
  • The central nervous system's (CNS) role in these limitations is understudied, hindering pathophysiology understanding and treatment development.
  • Investigating CNS contributions can guide future interventions to improve older adult mobility.

Purpose of the Study:

  • To foster research translation for interventions improving older adult mobility.
  • To address the understudied role of the central nervous system (CNS) in mobility limitations.
  • To facilitate the development of effective treatments for mobility impairments.

Main Methods:

  • A conference series was initiated in collaboration with the National Institute on Aging and the University of Pittsburgh.
  • The series began at the 2012 conference of the Gerontological Society of America.
  • The primary objective is to translate research findings into practical interventions.

Main Results:

  • Evidence supports the CNS as a key factor in mobility limitations among older adults without diagnosed neurological conditions.
  • Future research priorities include developing integrated models of aging and disease, quantifying CNS contributions to mobility loss, and promoting interdisciplinary collaboration.
  • Addressing methodological challenges, such as real-world mobility measurement and life-course perspectives, is crucial.

Conclusions:

  • Enhanced cross-disciplinary research is essential for understanding complex, multisystem associations in aging.
  • New training approaches are needed for clinicians and researchers, integrating diverse concepts and methodologies.
  • Focusing on emerging techniques and preparing investigators for complex assessments will advance the field.