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Physical activity and respiratory symptoms in children: the Generation R Study
Lisa M Driessen1, Jessica C Kiefte-de Jong, Vincent W V Jaddoe
1The Generation R Study Group, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Pediatrics, Erasmus Medical Center, Rotterdam, The Netherlands.
Insights
Physical activity in early childhood does not appear to impact the development of common respiratory symptoms like wheezing or shortness of breath in preschool years. This finding suggests limited influence of early physical activity on later respiratory health outcomes.
Area of Science:
- Pediatric Health
- Respiratory Medicine
- Epidemiology
Background:
- Investigating the link between early-life physical activity and subsequent respiratory health is crucial for understanding childhood development.
- The pre-school period is a critical window for respiratory health development.
Purpose of the Study:
- To determine the association between physical activity levels in the second year of life and the incidence of respiratory symptoms during the pre-school years.
- To explore the relationship between different intensities of physical activity and respiratory symptom development.
Main Methods:
- A prospective birth-cohort study (Generation R Study) in the Netherlands.
- Objective measurement of physical activity using accelerometers in 347 children at mean age 25.1 months.
- Standardized questionnaires (International Study of Asthma and Allergies in Childhood) assessed respiratory symptoms (wheezing, shortness of breath) at ages three and four years.
Main Results:
- No statistically significant association was found between total physical activity levels in the second year of life and wheezing symptoms in the third and fourth years of life.
- Similarly, physical activity levels did not show a significant association with shortness of breath symptoms in the pre-school period.
- Odds ratios for wheezing and shortness of breath remained close to 1.0, with confidence intervals crossing the null value.
Conclusions:
- Physical activity in the second year of life does not appear to be a significant determinant of common respiratory symptoms in pre-school children.
- These findings suggest that early-life physical activity may not play a major role in the development of respiratory issues during early childhood.
- Further research may explore other environmental or genetic factors influencing pre-school respiratory health.
Background:
To assess the relationship between physical activity in second year of life and respiratory symptoms during the pre-school period.
Methods:
This study was embedded in the Generation R Study, a large prospective birth-cohort study in Rotterdam, the Netherlands. Physical activity was measured in the second year of life by an Actigraph accelerometer in a subgroup of 347 children (182 boys, 165 girls; mean age 25.1 months) and data were expressed as counts per 15 sec in categories: light activity (302-614 counts/15 sec), moderate activity (615-1,230 counts/15 sec), and vigorous activity (≥1,231 counts/15 sec). Respiratory symptoms were assessed by the International Study of Asthma and Allergies in Childhood Questionnaire in the third and fourth year of life.
Results:
Physical activity levels were not associated with wheezing symptoms in the third and fourth year of life (OR: 0.98; 95% CI: 0.92-1.05 and OR: 0.99; 95% CI: 0.92-1.07 for total activity, respectively), nor associated with shortness of breath symptoms (OR: 0.98; 95% CI: 0.92-1.05 and OR 1.03; 95% CI: 0.96-1.11 for total activity, respectively).
Conclusion:
These results suggest that physical activity may not play an important role in the development of respiratory symptoms in pre-school children.
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