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Updated: May 9, 2026
12:18
An Allelotyping PCR for Identifying Salmonella enterica serovars Enteritidis, Hadar, Heidelberg, and Typhimurium
Published on: July 22, 2011
Diversity among human non-typhoidal salmonellae isolates from Zimbabwe
Bianca Paglietti1, Giovanni Falchi, Peter Mason
1Microbiologica, Dipartimento di Scienze Biomediche, Universita di Sassari, Sassari, Sardegna, Italy.
Summary
Non-typhoidal Salmonella infections pose a significant threat in sub-Saharan Africa. This study identified diverse Salmonella strains, including a multidrug-resistant Salmonella Isangi, highlighting the need for further research to control spread.
Area of Science:
- Microbiology
- Epidemiology
- Public Health
Background:
- Non-typhoidal Salmonella infections are a major public health concern in sub-Saharan Africa.
- These infections can lead to invasive disease, particularly in children and individuals with HIV.
Purpose of the Study:
- To investigate the epidemiology of Salmonella infections in southern Africa.
- To characterize Salmonella strains circulating in the region.
Main Methods:
- Serotyping, phage typing, and multilocus sequence typing were used.
- 167 non-typhoidal Salmonella strains from human clinical specimens (1995-2000) were analyzed.
Main Results:
- Salmonella Typhimurium DT56/ST313, Salmonella Enteritidis PT4, and Salmonella Isangi ST216 were the most common serovars.
- Salmonella Isangi isolates exhibited multidrug resistance, including to extended-spectrum cephalosporins.
- Twelve new sequence types and six new serotypes of Salmonella were identified.
Conclusions:
- Significant diversity of Salmonella enterica variants exists in Zimbabwe and sub-Saharan Africa.
- A multidrug-resistant Salmonella Isangi strain was confirmed in Zimbabwe.
- Further characterization of Salmonella Isangi is crucial for effective control strategies in sub-Saharan Africa.
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