CFS in Children and Adolescent: Ten Years of Retrospective Clinical Evaluation
Irene Elgen1, Omar Hikmat, Tora N Aspevik
1Department of Child and Adolescent Psychiatry, Haukeland University Hospital, 5021 Bergen, Norway ; Department of Clinical Medicine, University of Bergen, P.O Box 7804, 5020 Bergen, Norway.
Insights
An increasing number of children are evaluated for chronic fatigue syndrome (CFS). A systematic, multidisciplinary approach is essential for accurate diagnosis and care.
Area of Science:
- Pediatrics
- Neurology
- Infectious Diseases
Background:
- Chronic Fatigue Syndrome (CFS) diagnosis in pediatric populations presents unique challenges.
- Understanding the epidemiology and clinical characteristics of pediatric CFS is crucial for effective management.
Purpose of the Study:
- To estimate the number of children diagnosed with chronic fatigue syndrome (CFS).
- To analyze the clinical presentation and outcomes of pediatric CFS cases.
Main Methods:
- Retrospective data collection over 10 years (2002-2011) from children referred for fatigue symptoms.
- Analysis of diagnostic codes, patient history, infection markers, and anthropometric data.
Main Results:
- 27 children received a CFS diagnosis (G93.3) after exclusions.
- Most cases reported fatigue onset post-infection (Epstein-Barr virus, cytomegalovirus, or borrelia).
- Underweight (BMI < 17.5) was noted in 44% of patients; 59% were boys.
Conclusions:
- There is an observed increase in pediatric CFS evaluations.
- Systematic clinical assessment, including nutritional, eating disorder, and psychosocial factors, is vital.
- A multidisciplinary approach and European guidelines are needed for pediatric CFS assessment.
Abstract:
Aim. To estimate number of children being diagnosed with chronic fatigue syndrome (CFS). Methods. For a period of 10 years (2002-2011) data from children being referred for fatigue symptoms were collected retrospectively. Results. Thirty-seven children were referred. Four were excluded due to incorrect coding. Six (18%) patients received other diagnoses at the end of evaluation time. Of the 27 who received the diagnosis G93.3, four had a previous chronic illness, while 23 patients were previously healthy. All patients reported onset of fatigue symptom in relation to an infection, and all tested positive for IgG to either Epstein-Barr virus, cytomegalovirus or borrelia, indicating previous infection. There were 16 (59%) boys among the 27 patients. The mean age at the debut of fatigue symptoms was 141 months (SD 30) for boys and 136 months (SD 31) for girls, respectively. Being underweight, defined as BMI < 17.5, was found in 12 (44%) patients. Conclusion. An increasing number of children and adolescents are evaluated for CFS. The clinical assessment of children and adolescents with possible CFS need systematically evaluation. Nutritional status, possible eating disorder, and psychosocial issues need to be addressed and evaluated carefully. A multidisciplinary approach is essential when assessing CFS in children and adolescents. There is a need for European guidelines.
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