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Hypertension in sickle cell disease

C Narasimhan1, T George, J T George

  • 1Department of Medicine Unit-I, CMC Hospital, Vellore, Tamil Nadu.

The Journal of the Association of Physicians of India
|June 1, 1990
PubMed

We report a young male with sickle cell trait who developed severe hypertension and splenic infarction soon after travel to a high altitude. Hypertension persisted for three days after a diagnostic laparotomy. His blood pressure then continued to be normal over the next one and a half years. Red cell sludging in the small vessels of the kidney possibly activated the renin angiotensin system.

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