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Related Concept Videos

Metal-Ligand Bonds02:51

Metal-Ligand Bonds

The hemoglobin in the blood, the chlorophyll in green plants, vitamin B-12, and the catalyst used in the manufacture of polyethylene all contain coordination compounds. Ions of the metals, especially the transition metals, are likely to form complexes.
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
Complexometric Titration: Ligands00:43

Complexometric Titration: Ligands

Different monodentate and polydentate ligands are used as complexing agents in complexometric titration reactions. The formation of complexes by mono- and bidentate ligands involves two or more intermediate steps, limiting their use as complexing agents. In comparison, polydentate ligands can form complexes with metal ions in a single-step process, facilitating sharper end points. This means polydentate ligands, such as amino carboxylic acid derivatives, are most commonly employed in...
Cooperative Allosteric Transitions01:58

Cooperative Allosteric Transitions

Cooperative allosteric transitions can occur in multimeric proteins, where each subunit of the protein has its own ligand-binding site. When a ligand binds to any of these subunits, it triggers a conformational change that affects the binding sites in the other subunits; this can change the affinity of the other sites for their respective ligands. The ability of the protein to change the shape of its binding site is attributed to the presence of a mix of flexible and stable segments in the...
Ligand Binding Sites02:40

Ligand Binding Sites

Proteins are dynamic macromolecules that carry out a wide variety of essential processes; however, the activities of most proteins depend on their interactions with other molecules or ions, known as ligands.
Protein-ligand interactions are quite specific; even though numerous potential ligands surround a cellular protein at any given time, only a particular ligand can bind to that protein. Moreover, a ligand binds only to a dedicated area on the surface of the protein, known as the...
Ligand Binding and Linkage00:49

Ligand Binding and Linkage

Allosteric proteins have more than one ligand binding site; the binding of a ligand to any of these sites influences the binding of ligands to the other sites. When a protein is allosteric, its binding sites are called coupled or linked.  In the case of enzymes, the site that binds to the substrate is known as the active site and the other site is known as the regulatory site. When a ligand binds to the regulatory site, this leads to conformational changes in the protein that can influence the...
Valence Bond Theory02:42

Valence Bond Theory

Coordination compounds and complexes exhibit different colors, geometries, and magnetic behavior, depending on the metal atom/ion and ligands from which they are composed. In an attempt to explain the bonding and structure of coordination complexes, Linus Pauling proposed the valence bond theory, or VBT, using the concepts of hybridization and the overlapping of the atomic orbitals. According to VBT, the central metal atom or ion (Lewis acid) hybridizes to provide empty orbitals of suitable...

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Related Experiment Video

Updated: May 9, 2026

Discovery and Synthesis Optimization of Isoreticular Al(III) Phosphonate-Based Metal-Organic Framework Compounds Using High-Throughput Methods
07:20

Discovery and Synthesis Optimization of Isoreticular Al(III) Phosphonate-Based Metal-Organic Framework Compounds Using High-Throughput Methods

Published on: October 6, 2023

Carboxylate-functionalized phosphomolybdates: ligand-directed conformations.

Donghui Yang1, Suzhi Li, Pengtao Ma

  • 1Henan Key Laboratory of Polyoxometalate, Institute of Molecular and Crystal Engineering, College of Chemistry and Chemical Engineering, Henan University, Kaifeng 475004, Henan, China.

Inorganic Chemistry
|July 13, 2013
PubMed
Summary
This summary is machine-generated.

Novel polyanions were constructed using phosphomolybdates and carboxylate linkers. The self-assembly process is guided by the type and number of carboxyl groups in the carboxylic acids, influencing the final structure and properties.

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Surface Functionalization of Metal-Organic Frameworks for Improved Moisture Resistance
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Discovery and Synthesis Optimization of Isoreticular Al(III) Phosphonate-Based Metal-Organic Framework Compounds Using High-Throughput Methods
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Surface Functionalization of Metal-Organic Frameworks for Improved Moisture Resistance
08:12

Surface Functionalization of Metal-Organic Frameworks for Improved Moisture Resistance

Published on: September 5, 2018

Area of Science:

  • Inorganic Chemistry
  • Materials Science
  • Supramolecular Chemistry

Background:

  • Polyoxometalates (POMs) are versatile inorganic clusters with tunable properties.
  • Self-assembly is a key strategy for constructing complex molecular architectures.
  • Carboxylic acids can act as organic linkers in the formation of POM-based materials.

Purpose of the Study:

  • To synthesize novel polyanions by combining phosphomolybdate units with carboxylate linkers.
  • To investigate the role of carboxylic acids in templating the self-assembly process.
  • To characterize the stability and photochromic properties of the synthesized compounds.

Main Methods:

  • One-pot synthesis using ammonium heptamolybdate tetrahydrate, phosphorous acid, and various carboxylic acids.
  • Electrospray ionization mass spectrometry (ESI-MS) for stability analysis.
  • (31)P Nuclear Magnetic Resonance ((31)P NMR) spectroscopy for structural characterization.
  • Electron Paramagnetic Resonance (EPR) spectroscopy to study photochromic properties.

Main Results:

  • Four novel polyanion complexes were successfully synthesized and characterized.
  • The nature and number of carboxyl groups in carboxylic acids critically influence the self-assembly and structure of the POMs.
  • The synthesized POM clusters exhibit stability and interesting photochromic behavior.

Conclusions:

  • The judicious choice of carboxylic acids enables the rational design and synthesis of diverse polyanion structures.
  • The templating role of carboxylic acids in POM self-assembly is confirmed.
  • The study highlights the potential of these novel POMs for applications involving photochromism.