Related Experiment Video
Updated: May 9, 2026

Spontaneous Murine Model of Anaplastic Thyroid Cancer
Published on: February 3, 2023
"Hidden" bone metastasis from thyroid carcinoma: a clinical note
C Sioka1, M C Skarulis2, M K Tulloch-Reid3
1Nuclear Medicine Division, Department of Radiology and Imaging Sciences, Bethesda, MD, USA.
Abstract:
The (131)I-iodide ((131)I) whole-body scan, for thyroid carcinoma is at times difficult to interpret. In a diagnostic whole body (131)I scan of a patient with follicular carcinoma, a posterior skull lesion was partially hidden by overlapping facial structures. On lateral head view, the abnormality was clearly evident. SPECT/CT and MRI showed the lesion originated in the occipital bone and had enlarged into the posterior fossa. The mass was surgically removed and the patient received (131)I therapy for residual tissue. The study demonstrates a pitfall in the reading of two dimensional radioiodine images which can be overcome by SPECT or lateral imaging.
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