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Related Concept Videos

Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Related Experiment Video

Updated: May 9, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
06:29

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Published on: June 11, 2019

Advances in parametric mapping with CMR imaging.

Michael Salerno1, Christopher M Kramer

  • 1Cardiovascular Division, Department of Medicine, University of Virginia Health System, Charlottesville, VA 22908, USA.

JACC. Cardiovascular Imaging
|July 13, 2013
PubMed
Summary
This summary is machine-generated.

Cardiac magnetic resonance imaging (CMR) parametric mapping offers advanced assessment of heart function. New techniques quantify myocardial perfusion and relaxation times, aiding diagnosis of heart conditions.

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Last Updated: May 9, 2026

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Published on: May 31, 2024

Area of Science:

  • Cardiovascular Imaging
  • Medical Physics
  • Biomedical Engineering

Background:

  • Cardiac magnetic resonance imaging (CMR) is the gold standard for assessing myocardial volumes, function, and fibrosis.
  • Advancements enable rapid parametric mapping of myocardial perfusion and relaxation properties (T1, T2, T2*).

Purpose of the Study:

  • To review current and emerging applications of CMR parametric mapping for myocardial assessment.
  • To discuss the limitations and potential of quantitative perfusion and relaxation time imaging.

Main Methods:

  • Parametric mapping involves acquiring multiple images with varying sensitivity to a parameter.
  • Signal intensities are fitted to a model to generate parametric maps of perfusion or relaxation times.
  • Specialized rapid acquisition techniques are required for breath-hold imaging.

Main Results:

  • Quantitative perfusion imaging accurately determines myocardial ischemia and microvascular disease.
  • T1 mapping quantifies diffuse myocardial fibrosis and infiltration.
  • T2 and T2* mapping assess myocardial edema, inflammation, iron overload, and hemorrhage.

Conclusions:

  • CMR parametric mapping significantly expands the assessment of unique myocardial tissue parameters.
  • Growing evidence supports the clinical utility of quantitative perfusion and relaxation time assessment.
  • Current techniques have limitations, but hold significant potential for future cardiac diagnostics.