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On-pump fibrillating heart mitral valve replacement with the SAPIEN™ XT transcatheter heart valve
Enrico Ferrari1, Lars Niclauss, Didier Locca
1Department of Cardiac Surgery, University Hospital of Lausanne, Lausanne, Switzerland.
Insights
A novel hybrid technique offers a less invasive option for mitral valve replacement in high-risk patients. This approach uses transcatheter stent-valves, reducing surgical risks for redo patients and those with prior aortic valve replacement.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Biomaterials Science
Background:
- Standard mitral valve replacement (MVR) poses significant risks, particularly extensive annular decalcification, in high-risk patient groups.
- High-risk redo sternotomy patients and those with prior transcatheter aortic valve implantation (TAVI) are vulnerable to calcific mitral valve disease.
- Minimally invasive and transcatheter techniques are needed to mitigate surgical risks and complexity in mitral valve interventions.
Observation:
- A hybrid technique involving transcatheter, balloon-expandable Sapien™ XT stent-valves was employed for mitral valve replacement.
- The procedure was performed via right thoracotomy and left atriotomy on an on-pump fibrillating heart.
- This approach was utilized in patients with calcified, degenerated mitral valves, including redo sternotomy and concomitant TAVI cases.
Findings:
- The described hybrid technique provides an attractive alternative to standard MVR for specific high-risk patient populations.
- This method potentially decreases surgical risk and technical complexity compared to conventional open-heart surgery.
- Successful implantation of transcatheter stent-valves in the mitral position was achieved.
Implications:
- This hybrid MVR approach may expand treatment options for complex mitral valve disease in high-risk surgical candidates.
- It highlights the potential of combining transcatheter valve technology with minimally invasive surgical approaches.
- Further research and clinical evaluation are warranted to establish the long-term efficacy and safety of this hybrid technique.
Abstract:
In some high-risk patients, standard mitral valve replacement can represent a challenging procedure, requiring a risky extensive decalcification of the annulus. In particular, high-risk redo patients and patients with a previously implanted transcatheter aortic valve, who develop calcific mitral disease, would benefit from the development of new, minimally invasive, transcatheter or hybrid techniques for mitral valve replacement. In particular, mixing transcatheter valve therapies and well-established minimally invasive techniques for mitral replacement or repair can help in decreasing the surgical risk and the technical complexity. Thus, placing transcatheter, balloon-expandable Sapien™ XT stent-valves in calcified, degenerated mitral valves through a right thoracotomy, a left atriotomy and on an on-pump fibrillating heart, represents an attractive alternative to standard surgery in redo patients, in patients with concomitant transcatheter aortic stent-valves in place and in patients with a high-risk profile. We describe this hybrid technique in detail.
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