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The Doppler effect has several practical, real-world applications. For instance, meteorologists use Doppler radars to interpret weather events based on the Doppler effect. Typically, a transmitter emits radio waves at a specific frequency toward the sky from a weather station. The radio waves bounce off the clouds and precipitation and travel back to the weather station. The radio frequency of the waves reflected back to the station appears to decrease if the clouds or precipitation are moving...
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Three-dimensional Optical-resolution Photoacoustic Microscopy
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Dove prism based rotating dual beam bidirectional Doppler OCT.

Cedric Blatter1, Séverine Coquoz, Branislav Grajciar

  • 1Center of Medical Physics and Biomedical Engineering, Medical University Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.

Biomedical Optics Express
|July 13, 2013
PubMed
Summary

This study introduces a new dual beam optical coherence tomography (OCT) method to accurately measure blood flow velocity in the retina, overcoming limitations of traditional Doppler OCT.

Keywords:
(110.4500) Optical coherence tomography(170.2655) Functional monitoring and imaging(170.4500) Optical coherence tomography(280.2490) Flow diagnostics

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Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Medical Imaging

Background:

  • Traditional Doppler Optical Coherence Tomography (OCT) is prone to motion artifacts due to Doppler angle dependency, limiting clinical accuracy.
  • Accurate measurement of absolute blood flow velocity is crucial for diagnosing and monitoring various ocular conditions.

Purpose of the Study:

  • To develop and validate a novel bidirectional dual beam OCT technique for accurate, angle-independent measurement of absolute blood flow velocity.
  • To overcome the limitations of conventional Doppler OCT in clinical settings.

Main Methods:

  • Implementation of a bidirectional dual beam Swept Source OCT system operating at 1060nm with a 100,000 A-Scans/s acquisition speed.
  • Utilized a novel rotating scanning scheme with a Dove prism to probe the volume from two distinct illumination directions.
  • Reconstructed true flow velocity independent of arbitrary vessel orientations using data from variable controlled incidence planes.

Main Results:

  • Successfully resolved pulsatile retinal absolute blood velocity using the developed system.
  • Demonstrated the capability to perform segment scans around the optic nerve head and circumpapillary scan time series for velocity measurements.
  • The bidirectional dual beam technique effectively compensated for Doppler angle variations.

Conclusions:

  • The novel bidirectional dual beam OCT system provides accurate and angle-independent measurement of absolute retinal blood flow velocity.
  • This technique holds significant potential for improving the clinical diagnosis and management of retinal vascular diseases.
  • Further validation in diverse clinical scenarios is warranted to establish its full diagnostic utility.