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Updated: May 9, 2026

Obtaining Cancer Stem Cell Spheres from Gynecological and Breast Cancer Tumors
Published on: March 1, 2020
[Cancer stem cells depend on their own niche]
Yoshihiro Kano1, Hideshi Ishii, Masamitsu Konno
1Dept. of Surgery, Graduate School of Medicine, Osaka University, Suita, Japan.
Abstract:
It is considered that cancer stem cells have the same characteristics as normal stem cells, such as drug-resistance, self-renewal, differentiation, and tissue-formation. Normal stem cells depend on their surroundings, a niche. Cancer stem cells may also depend on their own niche. Because cancer stem cells are resistant to present remedies, it is important to find a remedy targeting cancer stem cells. The remedy must not only target cancer stem cells themselves but also target the niche surrounding the cancer stem cells.
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