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Updated: May 9, 2026
14:04
Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria
Published on: May 8, 2013
Emerging drugs on methicillin-resistant Staphylococcus aureus.
Adamantia Liapikou1, Antoni Torres
1Sotiria Hospital, 3rd Respiratory Department, Mesogion 152, 11527, Athens, Greece. mliapikou@yahoo.com
Expert Opinion on Emerging Drugs
|July 16, 2013
Summary
New antibiotics are emerging to combat Methicillin-resistant Staphylococcus aureus (MRSA) infections. Novel glycopeptides and oral agents show promise for future MRSA treatment strategies, offering new therapeutic options.
Area of Science:
- Infectious Diseases
- Microbiology
- Pharmacology
Background:
- Methicillin-resistant Staphylococcus aureus (MRSA) is a significant cause of severe hospital and community-acquired infections.
- Current treatment options for MRSA are limited, primarily relying on glycopeptides and linezolid.
Purpose of the Study:
- To review current and emerging therapeutic agents for Methicillin-resistant Staphylococcus aureus (MRSA) infections.
- To assess the potential of new antimicrobial agents in the evolving landscape of MRSA treatment.
Main Methods:
- A comprehensive literature search was performed using PubMed and ClinicalTrials.gov.
- Keywords included 'MRSA', 'MRSA therapy', 'new antibiotics', 'vancomycin', 'oritavancin', 'ceftaroline', 'linezolid', and 'tigecycline' for English-language articles published between 2000 and 2013.
Main Results:
- Several new agents are under development for MRSA infections.
- Newer glycopeptides like dalbavancin and oritavancin offer extended half-lives for less frequent dosing.
- Oral agents such as iclaprim are being explored for outpatient MRSA therapy.
Conclusions:
- The optimal role for new MRSA agents in therapeutic regimens is still being established.
- Emerging treatments like long-acting glycopeptides and oral agents may expand outpatient treatment options.
- Individualized treatment decisions considering the patient, infection site, and therapy setting are crucial for effective MRSA management.
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