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Updated: May 9, 2026

SA-β-Galactosidase-Based Screening Assay for the Identification of Senotherapeutic Drugs
Published on: June 28, 2019
Slowing the aging process
Jocelyn Wiggins1, Markus Bitzer
1Division of Geriatrics, Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA. wiggi@umich.edu
Abstract:
Research into the aging process is very new. For many years aging was thought to be the natural and inevitable consequence of a life of wear and tear. The idea that aging could be influenced by the genetic code and had a modifiable biologic component is less than 20 years old. During this time, aging has come to be understood as a complex biologic process controlled by signaling pathways and transcription factors. Similar attitudes pervade the field of nephrology. Whether a decline in renal function with age represents normal aging or kidney disease is the subject of much debate.
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