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Related Concept Videos

Inhaled Medications01:23

Inhaled Medications

Inhaled medications are crucial for managing chronic obstructive pulmonary disease (COPD) and asthma. They are essential for effective treatment and control, ensuring optimal respiratory health and well-being. Inhaled medication delivers drugs directly to the lungs, providing a rapid onset of action and reducing systemic side effects compared to oral or injectable medications. Three primary types of inhalation devices are used to administer these medications: nebulizers, metered-dose inhalers...
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
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Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
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Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Additional Routes of Drug Administration01:18

Additional Routes of Drug Administration

Choosing the appropriate route of drug administration is significantly influenced by two key factors: the therapeutic objectives and the inherent properties of the drug being used.
Administering drugs via inhalation allows for the direct delivery of gaseous, volatile substances or droplets to different parts of the respiratory tract. One of the advantages of the inhalation route is the rapid absorption of drugs into the circulatory system, which is possible because of the large surface area of...

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Related Experiment Video

Updated: May 9, 2026

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System
07:28

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System

Published on: April 6, 2017

[Inhaled medication in pediatrics].

A Sapet1, M Oudyi, J-C Dubus

  • 1Unité de pneumologie pédiatrique, hôpital de la Timone, CHU Timone-Enfants, 264, rue Saint-Pierre, 13385 Marseille cedex 05, France.

Revue De Pneumologie Clinique
|July 16, 2013
PubMed
Summary
This summary is machine-generated.

Choosing the right inhaled medication device for children is crucial. Pressurized metered dose inhalers with spacers are recommended for younger children, while dry powder inhalers suit older children, and nebulizers are for specific severe cases.

Keywords:
AerosolAérosolChildDispositif d’inhalationEnfantInhalational deviceNebulizationNébulisation

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Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System
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Published on: March 30, 2017

Area of Science:

  • Pediatric Pulmonology
  • Respiratory Medicine
  • Pharmacology

Context:

  • Inhaled medications are essential for managing pediatric respiratory conditions.
  • Multiple device types exist, each with unique characteristics.
  • Optimal drug delivery in children requires careful device selection.

Purpose:

  • To provide a comprehensive overview of available inhaled medication devices for children.
  • To guide healthcare professionals in selecting the most appropriate device based on age and ability.
  • To highlight the advantages and disadvantages of each delivery system.

Summary:

  • Three primary device categories are discussed: pressurized metered dose inhalers (pMDIs) with spacers, dry powder inhalers (DPIs), and nebulizers.
  • For children under 6 years, pMDIs with valved holding spacers are the preferred initial choice.
  • DPIs can be considered for children over 6, contingent on their ability to use them effectively; nebulizers are reserved for specific severe indications or emerging uses.

Impact:

  • Facilitates evidence-based selection of inhaled therapy devices in pediatric patients.
  • Aims to improve treatment adherence and efficacy in children with respiratory diseases.
  • Informs clinical practice guidelines for pediatric respiratory care and medication delivery.