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Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling

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Published on: May 30, 2011

Arterial spin labeling (ASL) perfusion: techniques and clinical use.

J-C Ferré¹, E Bannier, H Raoult

¹CHU de Rennes, Department of Radiology, Hôpital Pontchaillou, 2, rue Henri-Le-Guilloux, 35033 Rennes cedex 9, France; Plateforme Neurinfo, CHU de Rennes, Hôpital Pontchaillou, 2, rue Henri-Le-Guilloux, 35033 Rennes cedex 9, France; INRIA, VisAGeS unité/projet U746, 35042 Rennes, France; INSERM VisAGeS unité/projet U746, UMR 6074, Irisa, Université Rennes 1, 35043 Rennes cedex, France.

Diagnostic and Interventional Imaging

|July 16, 2013

Summary

Arterial spin labeling (ASL) perfusion MRI quantifies blood flow non-invasively by labeling arterial blood protons. This review covers ASL principles, mapping quality, artifacts, and key brain and kidney applications.

Keywords:

Brain Kidney MRI Perfusion

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Last Updated: May 9, 2026

Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling

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Construction and Application of Cerebral Functional Region-Based Cerebral Blood Flow Atlas Using Magnetic Resonance Imaging-Arterial Spin Labeling

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Published on: May 31, 2024

Area of Science:

Radiology and Medical Imaging
Biomedical Engineering

Background:

Arterial spin labeling (ASL) perfusion is a non-invasive Magnetic Resonance Imaging (MRI) technique.
It quantifies tissue blood flow by magnetically labeling protons in arterial blood.
Unlike other methods, ASL does not require exogenous contrast agents.

Purpose of the Study:

To present the fundamental principles of ASL perfusion MRI, including labeling techniques and mapping strategies.
To define quality criteria for ASL-derived perfusion maps and highlight common artifacts.
To outline the primary applications of ASL in encephalic (brain) and renal (kidney) imaging.

Main Methods:

Review of ASL principles, focusing on radiofrequency pulse labeling of arterial blood water.
Discussion of various ASL labeling strategies (e.g., continuous, pseudo-continuous, pulsed).
Explanation of image acquisition and post-processing techniques for generating perfusion maps.

Main Results:

ASL provides quantitative tissue perfusion information without contrast agents.
Quality assessment criteria are crucial for reliable ASL mapping, with artifacts needing careful consideration.
Established ASL applications exist in neuroimaging and nephrology.

Conclusions:

ASL perfusion MRI is a valuable non-invasive tool for assessing tissue blood flow.
Understanding ASL principles and quality control is essential for accurate clinical interpretation.
Encephalic and renal applications demonstrate the clinical utility of ASL.