Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Functional Brain Systems: Limbic System01:15

Functional Brain Systems: Limbic System

The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep brain...
Physiology of Emotion01:20

Physiology of Emotion

The physiology of emotions is a multifaceted process involving the autonomic nervous system, brain structures, hormones, and neurotransmitters. This intricate interplay dictates how emotions manifest in the body and influence behavior.
Autonomic Nervous System
The autonomic nervous system (ANS) plays a critical role in emotional responses by regulating involuntary physiological functions. It consists of two main components: the sympathetic and parasympathetic systems. The sympathetic system...
Cognitive Theories: Lazarus Mediational Theory of Emotion01:17

Cognitive Theories: Lazarus Mediational Theory of Emotion

Richard Lazarus' cognitive mediational theory highlights the pivotal role of cognitive appraisal in shaping emotional responses. According to this theory, the evaluation of a stimulus — based on personal values, goals, beliefs, and expectations — mediates the emotional response. This appraisal process is immediate and often occurs unconsciously, influencing the intensity and nature of the resulting emotion.
Cognitive Appraisal and Emotional Response
Lazarus proposed that emotions are not solely...
Role of Amygdala in Memory01:16

Role of Amygdala in Memory

The amygdala is a small, almond-shaped structure responsible for processing and storing memories, particularly those linked to emotions like fear and stress. It plays an essential role in the brain's response to emotionally significant events and often enhances memory formation by triggering stress hormone release. The amygdala is vital for encoding and retrieving memories associated with fear or stress, a process that is adaptive by helping organisms avoid dangerous situations.
One of the...
Role of Cerebellum and Prefrontal Cortex in Memory01:14

Role of Cerebellum and Prefrontal Cortex in Memory

The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the cerebellum's...
The Influence of Cognition on Affect01:29

The Influence of Cognition on Affect

Cognition plays a pivotal role in shaping emotional experiences, as demonstrated by Schachter and Singer’s two-factor theory of emotion. According to this model, emotion arises from a combination of physiological arousal and cognitive interpretation. The body’s physiological response to stimuli is ambiguous and only gains emotional significance through cognitive labeling. For instance, an increased heart rate and adrenaline surge while standing near an attractive person may be interpreted as...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Individualised mapping of living human brain mitochondria by MRI reveals signatures of bioenergetic defects.

bioRxiv : the preprint server for biology·2026
Same author

Generating Synthetic MR Perfusion Maps From DWI and FLAIR in Acute Ischemic Stroke: Development and External Validation of a Deep Learning Model.

Stroke·2026
Same author

Neurovariability as a signature of adaptive brain function.

Brain structure & function·2026
Same author

Error unawareness as a driver of cognitive decline in individuals at risk for Alzheimer's disease.

Communications biology·2026
Same author

Evolution of the frontal aslant tract and implications for primate vocalization and human speech.

Nature communications·2026
Same author

Correction to: Ultra-low-field brain MRI morphometry: Test-retest reliability and correspondence to high-field MRI.

Imaging neuroscience (Cambridge, Mass.)·2026
Same journal

Peripheral Nervous System Involvement in Parkinson's Disease: Peripheral Neuropathy, Neuromuscular Junction Dysfunction, and Clinical Implications.

Neuroscience and biobehavioral reviews·2026
Same journal

Violence on the self: Exploring the intersection of trauma and identity among sexual and gender minorities from a neurobiological and developmental perspective to advance our understanding of PTSD, moral injury, and dissociation symptoms.

Neuroscience and biobehavioral reviews·2026
Same journal

Meaning in life and biological functioning: A multisystem synthesis and agenda for future research.

Neuroscience and biobehavioral reviews·2026
Same journal

Beyond Diagnosis: Why and How Virtual Reality Should be Used in Research on Neurodevelopmental Conditions?

Neuroscience and biobehavioral reviews·2026
Same journal

What eye-movements tell us about Disorders of Consciousness?

Neuroscience and biobehavioral reviews·2026
Same journal

Systematic Review of Tactile-Based Interventions Combined with Multisensory Stimulation Protocols in the Rehabilitation of Patients with Disorders of Consciousness.

Neuroscience and biobehavioral reviews·2026
See all related articles

Related Experiment Video

Updated: May 9, 2026

Brain Imaging Investigation of the Memory-Enhancing Effect of Emotion
15:57

Brain Imaging Investigation of the Memory-Enhancing Effect of Emotion

Published on: May 4, 2011

A revised limbic system model for memory, emotion and behaviour.

Marco Catani1, Flavio Dell'acqua, Michel Thiebaut de Schotten

  • 1Natbrainlab, Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King's College London, UK.

Neuroscience and Biobehavioral Reviews
|July 16, 2013
PubMed
Summary
This summary is machine-generated.

This study updates the limbic model, identifying three distinct networks for memory, emotion, and self-thinking. This revised framework integrates current findings with anatomical data for limbic system disorders.

Keywords:
AmnesiaAntisocial behaviourAutism spectrum disorderBipolar disorderBrain networksDementiaDepressionEmotionLimbic systemMemoryObsessive–compulsive disorderSchizophreniaTractographyWhite matter connections

More Related Videos

Brain Imaging Investigation of the Neural Correlates of Emotion Regulation
14:04

Brain Imaging Investigation of the Neural Correlates of Emotion Regulation

Published on: August 26, 2011

Brain Imaging Investigation of the Neural Correlates of Emotional Autobiographical Recollection
11:30

Brain Imaging Investigation of the Neural Correlates of Emotional Autobiographical Recollection

Published on: August 26, 2011

Related Experiment Videos

Last Updated: May 9, 2026

Brain Imaging Investigation of the Memory-Enhancing Effect of Emotion
15:57

Brain Imaging Investigation of the Memory-Enhancing Effect of Emotion

Published on: May 4, 2011

Brain Imaging Investigation of the Neural Correlates of Emotion Regulation
14:04

Brain Imaging Investigation of the Neural Correlates of Emotion Regulation

Published on: August 26, 2011

Brain Imaging Investigation of the Neural Correlates of Emotional Autobiographical Recollection
11:30

Brain Imaging Investigation of the Neural Correlates of Emotional Autobiographical Recollection

Published on: August 26, 2011

Area of Science:

  • Neuroscience
  • Cognitive Neuroscience
  • Systems Neuroscience

Background:

  • The limbic system is crucial for emotion, memory, and behavior.
  • Existing limbic models require updating to incorporate recent findings.

Purpose of the Study:

  • To propose a revised, network-based model of the limbic system.
  • To integrate functional imaging and anatomical data for limbic system disorders.

Main Methods:

  • Review and synthesis of existing literature on limbic system anatomy and function.
  • Identification of distinct, overlapping functional networks within the limbic system.
  • Connectomic analysis to identify key cortical hubs.

Main Results:

  • Identification of three distinct, partially overlapping limbic networks: memory/spatial orientation, emotion/visceral integration, and self-directed thought.
  • Recognition of shared cortical nodes as principal hubs across these networks.
  • Reconciliation of functional imaging data with anatomical findings in limbic pathology.

Conclusions:

  • The revised limbic network model provides a more comprehensive understanding of brain function.
  • This model aids in explaining clinical disorders associated with limbic system dysfunction.
  • The identified networks offer new insights into the neural basis of cognition and emotion.