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Updated: May 9, 2026
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Published on: February 10, 2020
Evaluation of a commercially available carbohydrate deficient transferrin kit to detect beta-2-transferrin in
Karina Rodríguez-Capote1, Joceline Turner, Joseph Macri
1Department of Pathology and Laboratory Medicine, McMaster University, Ontario, Canada; Hamilton Regional Medicine Program, Ontario, Canada.
Objective:
The aim of this study was to evaluate the CEofix™ CDT Capillary Electrophoresis (CE) kit for the detection of β-2-tranferrin (β-2-Tf) in cerebrospinal fluid (CSF).
Design And Method:
Evaluation was performed according to CLSI EP5-A and EP12-A guidelines.
Results:
The method resolved β-2-Tf from other Tf isoforms. The C50 for β-Tf was determined to be 0.46 mg/L. Neither hemoglobin nor bilirubin co-migrated with β-2-Tf.
Conclusions:
The CDT kit can be used for detecting β-2-Tf in CSF by CE.
