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Error-promoting DNA synthesis in ovarian cancer cells

Heqiao Dai1, Robert J Hickey, Jianying Liu

  • 1Indiana University School of Medicine, Department of Medicine, Division of Clinical Pharmacology, USA.

Gynecologic Oncology
|July 16, 2013
PubMed
Summary

Ovarian cancer cells exhibit an error-prone DNA replication process, contributing to genetic damage. This altered DNA synthesis, not increased activity, leads to more replication errors, impacting ovarian cancer development.

Keywords:
DNA replicationMultiprotein complexOvarian cancerReplication fidelity

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