Shigella takes the temperature
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Updated: May 9, 2026

Epithelial Cell Infection Analyses with Shigella
Published on: February 9, 2024
1Veterinary Science and Microbiology; University of Arizona, Tucson, AZ, USA. vkv@email.arizona.edu
Abstract:
For bacteria, temperature is a fairly reliable cue for entry into a vertebrate host. Many pathogenic bacteria sense elevated temperatures (37°C) and turn on virulence and metabolic genes appropriate for survival and growth within the host. A recent study demonstrated that the expression of a heme uptake protein in Shigella dysenteriae and pathogenic Escherichia coli was dependent on an RNA thermometer.
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