Related Experiment Video
Updated: May 9, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
Early neurodevelopment in infants with deformational plagiocephaly
Sarah J Knight1, Vicki A Anderson, John G Meara
1Psychological Sciences and †Department of Paediatrics, University of Melbourne, Parkville, Victoria, Australia. sarah.knight@mcri.edu.au
Infants with deformational plagiocephaly (DP) often show weaker motor skills, particularly males. While not causing developmental issues, DP may signal a risk, highlighting the need for developmental screening.
Area of Science:
- Pediatric neurodevelopment
- Infant motor development
- Cranial orthotics
Background:
- Deformational plagiocephaly (DP) is a common condition in infants.
- Early identification of potential developmental impacts is crucial for intervention.
- Understanding the neurodevelopmental profile associated with DP is important for clinical practice.
Purpose of the Study:
- To characterize the early neurodevelopmental profile of Australian infants diagnosed with deformational plagiocephaly (DP).
- To assess cognitive and motor skills in infants with DP before initiating treatment.
- To identify any significant differences in neurodevelopmental outcomes between infants with DP and the general population.
Main Methods:
- Utilized the Bayley Scales of Infant Development, Second Edition, for assessment.
- Recruited 21 infants with a confirmed DP diagnosis (mean age 7.9 months).
- Compared the neurodevelopmental scores of infants with DP to normative population data.
Main Results:
- Infants with DP, as a group, demonstrated significantly weaker motor skills compared to normative data.
- No significant differences were found in cognitive abilities between infants with DP and the normative population.
- Male infants with DP exhibited significantly reduced motor abilities compared to female infants with DP.
Conclusions:
- Deformational plagiocephaly (DP) itself does not appear to cause developmental problems.
- DP may serve as a potential marker indicating a risk for developmental concerns.
- Routine developmental screening is recommended for infants diagnosed with DP to identify potential issues early.
More Related Videos
07:40Generation of iPSC-derived Human Brain Organoids to Model Early Neurodevelopmental Disorders
Published on: April 14, 2017
08:03Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Related Concept Videos
Neurulation
Sutures of the Skull
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...