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Related Experiment Video

Updated: May 9, 2026

Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection

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Orofacial digital syndrome.

Kajal V Dave¹, Shilpa C Patel, Bhavin B Dudhia

¹Department of Oral Pathology and Microbiology, Ahmedabad Dental College and Hospital, Ahmedabad, Gujrat, India.

Indian Journal of Dental Research : Official Publication of Indian Society for Dental Research

|July 16, 2013

Summary

This summary is machine-generated.

This case study presents a 10-year-old boy with delayed permanent teeth eruption, exhibiting features of Orofacial Digital Syndrome (OFDS). The study compares clinical and radiological aspects of OFDS types I and II, including chromosomal analysis.

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Area of Science:

Dentistry
Genetics
Pediatrics

Background:

Orofacial Digital Syndrome (OFDS) is a rare congenital disorder affecting facial and limb development.
Delayed eruption of permanent teeth is a recognized, though less common, manifestation of OFDS.

Observation:

A 10-year-old male presented with delayed permanent teeth eruption.
The patient displayed classical clinical and radiological features consistent with Orofacial Digital Syndrome.

Findings:

The case highlights the orofacial and digital anomalies characteristic of OFDS.
Comparative analysis of clinico-radiological features between OFDS type I and type II was performed.
Chromosomal karyotyping was conducted to further investigate the genetic basis.

Implications:

This report expands the understanding of OFDS manifestations, particularly dental anomalies.
It underscores the importance of comprehensive evaluation in diagnosing OFDS.
Further research into genotype-phenotype correlations in OFDS is warranted.