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Updated: May 9, 2026
04:41
Knee Arthrocentesis in Adults
Published on: February 25, 2022
Rivaroxaban is as efficient and safe as bemiparin as thromboprophylaxis in knee arthroscopy
L Muñoa1, A B González, P Díaz de Rada
1Department of Orthopaedic Surgery and Traumatology, School of Medicine, University of Navarre, Av. Pío XII 36, 31008, Pamplona, Spain, lmunoa@unav.es.
Musculoskeletal Surgery
|July 16, 2013
Summary
Rivaroxaban and bemiparin show similar effectiveness for preventing deep-vein thrombosis (DVT) after knee surgery. Extended prophylaxis with rivaroxaban for three weeks is a safe option, with one case of bleeding reported.
Area of Science:
- Orthopedic Surgery
- Pharmacology
- Vascular Medicine
Background:
- Knee arthroscopy carries a risk of deep-vein thrombosis (DVT).
- Extended prophylaxis may be necessary to mitigate this risk.
- Comparing anticoagulant options is crucial for patient safety and treatment efficacy.
Purpose of the Study:
- To compare the effectiveness and safety of rivaroxaban versus bemiparin.
- To evaluate 3-week extended prophylaxis after knee arthroscopy.
- To assess thromboprophylaxis outcomes in orthopedic surgery patients.
Main Methods:
- A comparative study involving 467 patients undergoing knee arthroscopy.
- Patients received either rivaroxaban or bemiparin for extended prophylaxis.
- Postoperative follow-up included clinical assessment and diagnostic tests for DVT at 1 and 3 months.
Main Results:
- No thromboembolic events were observed in either treatment group.
- One patient on rivaroxaban experienced epistaxis, leading to drug withdrawal.
- Both rivaroxaban and bemiparin demonstrated comparable safety and efficacy profiles.
Conclusions:
- Extended prophylaxis with rivaroxaban (10 mg once daily for 3 weeks) is as effective as bemiparin for knee arthroscopy.
- Rivaroxaban offers a safe and effective option for DVT prevention in this patient population.
- The findings support the use of rivaroxaban in extended thromboprophylaxis protocols.
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