Related Experiment Video
Updated: May 9, 2026

Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury
Published on: January 20, 2023
Update on post-traumatic stress syndrome after anesthesia.
1Department of Anesthesiology and Intensive Care, Catholic University of the Sacred Heart, Rome, Italy. pa.aceto@gmail.com
Surgical patients experiencing intraoperative awareness may develop post-traumatic stress disorder (PTSD). Early psychological assessment is crucial for detecting symptoms and preventing long-term psychological disability.
Area of Science:
- Anesthesiology
- Psychology
- Trauma Studies
Background:
- Intraoperative awareness during general anesthesia affects 0.5-2% of surgical patients.
- Awareness can lead to anxiety and potentially post-traumatic stress disorder (PTSD).
Purpose of the Study:
- To review the prevalence of PTSD following intraoperative awareness.
- To analyze patient complaints, and the type and timing of psychological assessments used.
Main Methods:
- Searched PubMed, MEDLINE, and The Cochrane Library up to October 2012.
- Included prospective and retrospective studies on adult human subjects detailing PTSD prevalence or psychological sequelae after awareness episodes.
Main Results:
- Seven studies identified a PTSD prevalence ranging from 0% to 71%.
- Acute emotions like fear and helplessness were significantly correlated with psychological sequelae, including PTSD.
- Psychological symptoms were reported from 2-6 hours to 30 days post-awakening; prior assessments lacked dissociation evaluation.
Conclusions:
- Psychological assessment, including at least three interviews at 2-6 hours, 2-36 hours, and 30 days, is recommended when intraoperative awareness is suspected.
- Future research should focus on detecting dissociative symptoms to enable prompt treatment and prevent long-term psychological disability.
Related Concept Videos
Post-traumatic Stress Disorder
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events, are a...
Stages of General Anesthesia
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Aneurysm IV: Nursing Management